KATNA1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 936 Sequence: atgagtcttc ttatgattag tgagaatgta aaattggctc gtgaatatgc attgctggga aactatgact ctgcgatggt ctattatcag ggagttcttg accaaatgaa caagtatctg tactcagtca aagatacata cctccagcag aaatggcaac aggtttggca ggaaataaat gtggaagcta aacatgttaa agatatcatg aaaacactag agagctttaa actggacagc actcccttga aagcggcaca gcatgacctt ccagcttctg agggagaagt ctggtccatg cctgtacctg ttgaacgaag accctcacca ggacctagaa aacgccaatc ttctcagtac agtgacccta aatcacatgg taatcgtcca agtacaactg tcagagttca ccgttcatct gcacagaatg ttcacaatga cagagggaaa gctgttcgtt gtcgtgaaaa gaaagaacag aataaaggaa gagaggaaaa gggagtactg atggtcggcc cacctggcac ggggaagacg ctccttgcta aagcagtagc tacagaatgc aagacaacat tcttcaatgt ctcttcatca actttgactt ccaaatacag aggagaatct gagaagcttg ttcgtcttct gtttgaaatg gctcgatttt attctccagc caccatattt attgatgaga tagactccat ctgtagtcgc cgagggactt ctgaagaaca tgaagcaagc agaagggtga aagcggagct gctggttcag atggatggtg ttggaggtac ttctgaaaat gatgaccctt ccaaaatggt tatggttctg gcagctacta attttccctg ggatatagat gaggctttaa gacgacgcct tgagaaacga atctatattc ctttgccgtc agggatgcgt Protein function: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth. [The UniProt Consortium]