IZUMO1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1053 Sequence: atggggccgc attttaccct cctgtgtgcg gcgctggccg gttgcttgct tcctgccgag gggtgtgtta tatgtgaccc gtctgtcgtg ctggcgctaa agtccctgga gaaagattac ctgcctggcc acctggatgc gaagcatcac aaagccatga tggaaagggt agagaatgcc gtgaaggatt tccaggaact gtcgcttaat gaggatgcct atatgggggt cgttgatgag gccacactgc aaaaggggtc ctggagtttg ctgaaggatc tgaaacgcat cacagacagt gatgtaaaag gcgatctctt tgtgaaggag ctattttgga tgttgcactt gcaaaaggaa acctttgcca cctatgttgc tcgattccaa aaagaggctt attgtcccaa caaatgtggt gtgatgttgc aaactctgat ctggtgcaag aactgcaaaa aggaggttca cgcttgtcga aagtcctacg attgcgggga gcggaatgtg gaagttcctc aaatggaaga catgatcctg gactgtgagt taaactggca tcaggcttcg gaaggcctca ctgattacag cttttacagg gtttggggga acaatacgga gaccttggtg tccaagggga aagaggccac cctgaccaag cccatggtgg gtccagagga tgcaggcagc taccgctgcg agctgggctc tgtgaattcc agcccagcca cgatcatcaa ttttcacgtc acagtgttgc ccaaaatgat caaggaggaa aaaccttctc caaatatcgt aaccccgggg gaggcgacca cggagtcgtc cataagcctc cagcctctgc agcccgagaa aatgctggca agccgccttc tggggctgct gatctgcggc tccctagcac tgataaccgg ccttaccttt gcgatatttc gtcgaaggaa ggtgatcgat ttcatcaaat cctcactgtt tggccttggc agtggagttg ccgagcaaac ccaggtccca aaagaaaagg ccacagattc gaggcaacaa Protein function: Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg (PubMed:15759005). The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:15759005). The ligand- receptor interaction probably does not act as a membrane 'fusogen' (PubMed:15759005). [The UniProt Consortium]