IRGM (Vector pUC, Accession No. BC128168)

Length: 537 Sequence: ATGAATGTTG AGAAAGCCTC AGCAGATGGG AACTTGCCAG AGGTGATCTC TAACATCAAG GAGACTCTGA AGATAGTGTC CAGGACACCA GTTAACATCA CTATGGCAGG GGACTCTGGC AATGGGATGT CCACCTTCAT CAGTGCCCTT CGAAACACAG GACATGAGGG TAAGGCCTCA CCTCCTACTG AGCTGGTAAA AGCTACCCAA AGATGTGCCT CCTATTTCTC TTCCCACTTT TCAAATGTGG TGTTGTGGGA CCTGCCTGGC ACAGGGTCTG CCACCACAAC CCTGGAGAAC TACCTGATGG AAATGCAGTT CAACCGGTAT GACTTCATCA TGGTTGCATC TGCACAATTC AGCATGAATC ATGTGATGCT TGCCAAAACC GCTGAGGACA TGGGAAAGAA GTTCTACATT GTCTGGACCA AGCTAGACAT GGACCTCAGC ACAGGTGCCC TCCCAGAAGT GCAGCTACTG CAGATCAGAG AAAATGTCCT GGAAAATCTC CAGAAGGAGC GGGTATGTGA Protein function: Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility. [The UniProt Consortium]