INPP5K (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1347 Sequence: atgagctcgc ggaagctgag cgggccgaaa ggcaggaggc tcagcataca cgtcgtgact tggaacgtgg cttcggcagc gccccctcta gatctcagtg acctgcttca gctgaacaac cggaacctca atcttgacat atatgttatt ggtttgcagg aattgaactc tgggatcata agcctccttt ccgatgctgc ctttaatgac tcgtggagca gtttcctcat ggatgtgctt tcccctctga gcttcatcaa ggtctcccat gtccgtatgc aggggatcct cttactggtc tttgccaagt atcagcattt gccctatatc cagattctgt ctactaaatc cacccccact ggcctgtttg ggtactgggg gaacaaaggt ggagtcaaca tctgcctgaa gctttatggc tactatgtca gcatcatcaa ctgccacctg cctccccaca tttccaacaa ttaccagcgg ctggagcact ttgaccggat cctggagatg cagaattgtg aggggcgaga catcccaaac atcctggacc acgacctcat tatctggttt ggagacatga actttcggat cgaggacttt gggttgcact ttgttcggga atccattaaa aatcggtgct acggtggcct gtgggagaag gaccagctca gcattgccaa gaaacatgac ccgctgctcc gggagttcca ggagggccgc ctactcttcc cgcccaccta caagtttgat aggaactcca acgactatga caccagtgag aaaaaacgca agcctgcatg gaccgatcgc atcctgtgga ggctgaagcg gcagccctgt gctggccccg acactcccat accgccggcg tcacacttct ccttgtctct gaggggctac agcagccaca tgacgtacgg catcagcgac cacaagcctg tctccggcac gttcgacttg gagctgaagc cattggtgtc tgctccgctg atcgtcctga tgcccgagga cctgtggacc gtggaaaatg acatgatggt cagctactct tcaacctcgg acttccccag cagcccgtgg gactggattg gactgtacaa ggtggggctg cgggacgtta atgactacgt gtcctatgcc tgggtcgggg acagcaaggt ctcctgcagc gacaacctga accaggttta catcgacatc agcaatatcc ctaccactga agatgagttt ctcctctgtt actacagcaa cagtctgcgt tctgtggtgg ggataagcag acccttccag atcccgcctg gctccttgag ggaggaccca ctgggtgaag cacagccaca Protein function: Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (PubMed:10753883, PubMed:16824732). Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate (PubMed:10753883). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases, therefore, is the specific regulator for insulin signaling in skeletal muscle. [The UniProt Consortium]