IFT122 (Vector pUC, Accession No. BC003045)

Length: 3396 Sequence: atgagggccg tgttgacgtg gagagataaa gccgagcact gtataaatga catcgcattt aagcctgatg gaactcaact gattttggct gccggaagca gattactggt ttatgacacc tctgatggca ccttacttca gcccctcaag ggacacaaag acactgtgta ctgtgtggca tatgcgaagg atgggttgtg gtctcctgaa cagaagtctg tctccaaaca caaatcaagc agcaagatca tctgctgcag ctggacaaat gatggtcagt acctggcgct ggggatgttc aatgggatca tcagcatacg gaacaaaaat ggcgaggaga aagtaaagat cgagcggccg gggggctccc tctcgccaat atggtccatc tgctggaacc cttcaagaga ggaacgtaat gacatcctgg ctgtggctga ctggggacag aaagtttcct tctaccagct gagtggaaaa cagattggaa aggatcgggc actgaacttt gacccctgct gcatcagcta ctttactaaa ggcgagtaca ttttgctggg gggttcagac aagcaagtat ctcttttcac caaggatgga gtgcggcttg ggactgttgg ggagcagaac tcctgggtgt ggacgtgtca agcgaaaccg gattccaact atgtggtggt cggctgccag gacggcacca tttccttcta ccagcttatt ttcagcacag tccatgggct ttacaaggac cgctatgcct acagggatag catgactgac gtcattgtgc agcacctgat cactgagcag aaagttcgga ttaaatgcaa agagcttgtc aagaagattg ccatctacag aaatcgattg gctatccaac tgccagagaa aatcctcatc tatgagttgt attcagagga cttatcagac atgcattacc gggtaaagga gaagattatc aagaagtttg agtgcaacct cctggtggtg tgtgccaatc acatcatcct gtgccaggag aaacggctgc agtgcctgtc cttcagcgga gtgaaggagc gggagtggca gatggagtct ctcattcgtt acatcaaggt gatcggtggc cctcctggaa gagaaggcct cttagtgggg ctgaagaatg gacagatcct gaagatcttc gtggacaatc tctttgctat cgtcctgctg aagcaggcca cagctgtgcg ctgcttggac atgagtgcct cccgtaagaa gctggccgtg gtagatgaaa atgacacttg cctggtgtat gacatcgaca ccaaggagct gctttttcag gaaccaaacg ccaacagtgt agcttggaac acccagtgtg aggacatgct ctgcttctcg ggaggaggct acctcaacat caaagccagc accttccctg tgcaccggca gaagctgcag ggctttgtgg tcggctacaa tggctccaag atcttctgcc tccatgtctt ctccatttct gccgtggagg tgccgcagtc cgctcccatg taccagtacc tggataggaa actgttcaag gaagcctacc agattgcttg cttgggtgtc acagacactg attggcgtga actggccatg gaagcgctag aaggtttaga ttttgaaact gcaaagaagg ccttcatcag agtacaagac ctccgatatt tagagctcat cagcagcatt gaggagagga agaagcgggg agagaccaac aatgacctgt ttctggcaga tgtgttttcc taccagggga agttccatga ggccgccaaa ctgtacaaga ggagtgggca cgagaacctc gcgcttgaaa tgtacaccga cctctgcatg tttgagtatg ccaaggattt ccttggatct ggagacccca aagaaacaaa gatgctaatc accaaacagg ctgactgggc cagaaatatc aaggagccca aagccgccgt ggagatgtac atctcagcag gagagcacgt caaggccatc gagatctgtg gtgaccatgg ctgggttgac atgttgatcg acatcgcccg caaactggac aaggctgagc gcgagcccct gctgctgtgc gctacctacc tcaagaagct ggacagccct ggctatgctg ctgagaccta cctgaagatg ggtgacctca agtccctggt gcagctgcac gtggagaccc agcgctggga tgaggccttt gctttgggtg agaagcatcc tgagtttaag gatgacatct acatgccgta tgctcagtgg ctagcagaga acgatcgctt tgaggaagcc cagaaagcgt tccacaaggc tgggcgacag agagaagcgg tccaggtgct ggagcagctc acaaacaatg ccgtggcgga gagcaggttt aatgatgctg cctattatta ctggatgctg tccatgcagt gcctcgatat agctcaagca gatcctgccc agaaggacac aatgcttggc aagttctacc acttccagcg tttggcagag ctgtaccatg gttaccatgc catccatcgc cacacggaag atccgttcag tgtccatcgt cctgaaactc ttttcaacat ctccaggttc ctgctgcaca gcctgcccaa ggacaccccc tcgggcatct ctaaagtgaa aatactcttc accttggcca agcagagcaa ggccctcggt gcctacaggc tggcccggca cgcctatgac aagctgcgtg gcctgtacat ccctgccaga ttccaaaagt ccattgagct gggtaccctg accatccgcg ccaagccctt ccacgacagt gaggagttgg tgcccttgtg ctaccgctgc tccaccaaca acccgctgct caacaacctg ggcaacgtct gcatcaactg ccgccagccc ttcatcttct ccgcctcttc ctacgacgtg ctacacctgg ttgagttcta cctggaggaa gggatcactg atgaagaagc catctccctc atcgacctgg aggtgctgag acccaagcgg gatgacagac agctagagat tgcaaacaac agctcccaga ttctgcggct agtggagacc aaggactcca tcggagatga ggacccgttc acagctaagc tgagctttga gcaaggtggc tcagagttcg tgccagtggt ggtgagccgg ctggtgctgc gctccatgag ccgccgggat gtcctcatca agcgatggcc cccacccctg aggtggcaat acttccgctc actgctgcct gacgcctcca ttaccatgtg cccctcctgc ttccagatgt tccattctga ggactatgag ttgctggtgc ttcagcatgg ctgctgcccc tactgccgca ggtgcaagga tgaccctggc Protein function: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking (PubMed:27932497, PubMed:29220510). Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia. [The UniProt Consortium]