IFFO1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 603 Sequence: atgggggggc ggaagcggga gcgcaaggct gccgtcgagg aggacacctc cctgtcggag agtgaggggc cccgccagcc cgatggggat gaggaggaga gcacagccct cagcatcaac gaggagatgc agcgcatgct caaccagctg agggagtatg attttgagga cgactgtgac agcctgactt gggaggagac tgaggagacc ctgctgcttt gggaggattt ctcaggctat gccatggcag ctgcagaggc ccagggagag cagcaggaag atagcctgga gaaggtgatt aaagatacgg agtccctgtt caaaacccgg gagaaggagt atcaggagac cattgaccag atagagctgg agttggccac ggccaagaac gacatgaacc ggcacctgca cgagtacatg gagatgtgca gcatgaagcg cggcctggac gtgcagatgg agacctgccg ccggctcatc acccagtctg gagaccgaaa gtctcctgct ttcactgcgg tcccgcttag cgacccgccg ccgccgccaa gcgaggctga ggactccgat cgcgatgtct catctgacag ctccatgaga Protein function: Nuclear matrix protein involved in the immobilization of broken DNA ends and the suppression of chromosome translocation during DNA double-strand breaks (DSBs) (PubMed:31548606). Interacts with the nuclear lamina component LMNA, resulting in the formation of a nucleoskeleton that relocalizes to the DSB sites in a XRCC4-dependent manner and promotes the immobilization of the broken ends, thereby preventing chromosome translocation (PubMed:31548606). Acts as a scaffold that allows the DNA repair protein XRCC4 and LMNA to assemble into a complex at the DSB sites (PubMed:31548606). [The UniProt Consortium]