Human, ST8SIA1 cDNA ORF Clone in Cloning Vector

Human, ST8SIA1 cDNA ORF Clone in Cloning Vector
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SNB-HG15646-G 1 each -

10 - 15 business days*

82.00€
 
Protein Function: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid... more
Product information "Human, ST8SIA1 cDNA ORF Clone in Cloning Vector"
Protein Function: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3, gangliosides are a subfamily of complex glycosphingolipds that contain one or more residues of sialic acid (PubMed:18348864, PubMed:22885356, PubMed:7937974, PubMed:8058740, PubMed:8195250, PubMed:8631981, PubMed:8706663). Can catalyze the addition of a second alpha-2,8-sialic acid to GD3 to form GT3 (PubMed:8631981). Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (PubMed:8706663). Can synthesize unusual tetra- and pentasialylated lactosylceramide derivatives identified as GQ3 (II3Neu5Ac4-Gg2Cer) and GP3 (II3Neu5Ac5-Gg2Cer) in breast cancer cells (PubMed:22885356) [The Uniprot Consortium]
Keywords: ST8SIA1, Sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase St8Sia I, Alpha-2,8-sialyltransferase 8A, Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Supplier: Sino Biological
Supplier-Nr: HG15646-G

Properties

Species reactivity: human

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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