Human, SerpinD1 cDNA ORF Clone in Cloning Vector

Protein Function: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner , Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils , Shows negligible inhibition, in vitro, of thrombin and tPA and no inhibition of factor Xa, in vitro [The Uniprot Consortium]