Human, MTM1/myotubularin 1 cDNA ORF Clone in Cloning Vector

Human, MTM1/myotubularin 1 cDNA ORF Clone in Cloning Vector
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
SNB-HG15039-G 1 each -

10 - 15 business days*

82.00€
 
Protein Function: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate... more
Product information "Human, MTM1/myotubularin 1 cDNA ORF Clone in Cloning Vector"
Protein Function: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) (PubMed:10900271, PubMed:11001925, PubMed:12646134, PubMed:14722070). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides (PubMed:9537414). Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome (PubMed:14722070). Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture (PubMed:21135508). Plays a role in mitochondrial morphology and positioning (PubMed:21135508). Required for skeletal muscle maintenance but not for myogenesis (PubMed:21135508). In skeletal muscles, stabilizes MTMR12 protein levels (PubMed:23818870) [The Uniprot Consortium]
Keywords: MTM1, Myotubularin, Phosphatidylinositol-3-phosphate phosphatase, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase
Supplier: Sino Biological
Supplier-Nr: HG15039-G

Properties

Species reactivity: human

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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