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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| SNB-HG14712-G | 1 each | - |
10 - 15 business days* |
82.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Function: Transcriptional repressor which binds preferentially to the canonical E box... more
Product information "Human, HEY1 cDNA ORF Clone in Cloning Vector"
Protein Function: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737) [The Uniprot Consortium]
| Keywords: | HEY1, HES-related repressor protein 1, Hairy-related transcription factor 1, Cardiovascular helix-loop-helix factor 2, Class B basic helix-loop-helix protein 31, Hairy and enhancer of split-related protein 1, Hairy/enhancer-of-split related with YRPW moti |
| Supplier: | Sino Biological |
| Supplier-Nr: | HG14712-G |
Properties
| Species reactivity: | human |
Database Information
| KEGG ID : | K09091 | Matching products |
| UniProt ID : | Q9Y5J3 | Matching products |
| Gene ID : | GeneID 23462 | Matching products |
Handling & Safety
| Storage: | +20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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