Human, CSEN cDNA ORF Clone in Cloning Vector

Human, CSEN cDNA ORF Clone in Cloning Vector
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Item number Size Datasheet Manual SDS Delivery time Quantity Price
SNB-HG14683-G 1 each -

10 - 15 business days*

82.00€
 
Protein Function: Calcium-dependent transcriptional repressor that binds to the DRE element of... more
Product information "Human, CSEN cDNA ORF Clone in Cloning Vector"
Protein Function: Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity) , Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner , May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of amyloid-beta formation [The Uniprot Consortium]
Keywords: KCNIP3, Calsenilin, DRE-antagonist modulator, Kv channel-interacting protein 3, A-type potassium channel modulatory protein 3
Supplier: Sino Biological
Supplier-Nr: HG14683-G

Properties

Species reactivity: human

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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