HSPBP1 (Vector pUC, Accession No. BC001236)

Length: 1089 Sequence: atgtcagacg aaggctcaag ggggagccgc ctgcccctgg cgctgccccc ggcctcccag ggttgctctt cagggggcgg cggcggcggc ggcggcggct cctcggctgg gggctcgggc aattcccggc ccccacgcaa cctccaaggc ttgctgcaga tggccatcac cgcgggctct gaagagccag accctcctcc agaaccgatg agtgaggaga ggcgtcagtg gctgcaggag gccatgtcgg ctgccttccg aggccagcgg gaggaggtgg agcagatgaa gagctgcctc cgagtgctgt cacagcccat gccccccact gctggggagg ccgagcaggc ggccgaccag caagagcgag agggggccct ggagctgctg gccgacctgt gtgagaacat ggacaatgcc gcagacttct gccagctgtc tggcatgcac ctgctggtgg gccggtacct ggaggcgggg gctgcgggac tgcggtggcg ggcggcacag ctcatcggca cgtgcagtca gaacgtggca gccatccagg agcaggtgct gggcctgggt gccctgcgta agctgctgcg gctgctggac cgcgacgcct gcgacacggt gcgcgtcaag gccctcttcg ccatctcctg tctggtccga gagcaggagg ctgggctgct gcagttcctc cgcctggacg gcttctctgt gttgatgagg gccatgcagc agcaggtgca gaagctcaag gtcaaatcag cattcctgct gcagaacctg ctggtgggcc accctgaaca caaagggacc ctgtgctcca tggggatggt ccagcagctg gtggccctgg tgcggacaga gcacagcccc ttccacgagc acgtgcttgg agccctgtgc agcctggtga cagactttcc gcagggtgtg cgcgagtgtc gggagccgga actgggcctg gaggagctcc tccgccaccg ctgtcagctg ctgcagcagc atgaggagta ccaggaggag ctggagttct gtgaaaagct gctacagacc tgtttctcca gcccagcgga cgacagcatg Protein function: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. [The UniProt Consortium]