HIST1H2BH (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or p

Length: 381 Sequence: ATGCCTGATC CAGCTAAGTC CGCTCCCGCC CCGAAGAAGG GCTCCAAGAA GGCGGTGACC AAGGCGCAGA AGAAGGATGG CAAGAAGCGT AAACGCAGCC GCAAGGAGAG CTACTCCGTA TACGTTTACA AGGTGCTGAA GCAAGTCCAC CCCGACACCG GCATCTCCTC CAAAGCCATG GGGATCATGA ATTCCTTTGT CAACGATATC TTCGAGCGCA TCGCCGGCGA GGCTTCCCGC CTGGCTCATT ACAACAAGCG TTCGACCATC ACCTCCAGGG AGATCCAGAC AGCCGTGCGC CTGCTGCTGC CTGGGGAACT GGCCAAGCAC GCCGTGTCCG AGGGCACTAA GGCCGTCACC AAGTACACCA GCTCCAAATA Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]