HIST1H2AH (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or p

Length: 387 Sequence: ATGTCTGGGC GTGGTAAGCA GGGCGGTAAA GCTCGCGCCA AGGCCAAGAC CCGCTCTTCT CGGGCTGGGC TTCAGTTCCC CGTGGGCCGA GTGCACCGCC TGCTCCGCAA GGGTAATTAT GCCGAGCGGG TTGGAGCCGG CGCGCCAGTG TACCTGGCTG CGGTGCTGGA GTACCTGACC GCTGAGATCC TGGAGCTGGC TGGCAATGCG GCCCGCGACA ACAAGAAGAC CCGTATCATC CCGCGTCACC TCCAACTGGC CATCCGCAAC GACGAGGAGC TCAACAAGCT GCTGGGCAAA GTCACCATCG CGCAGGGTGG TGTCTTGCCC AATATCCAGG CCGTGCTGCT GCCTAAGAAG ACTGAGAGCC ACCATAAGGC Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]