HIST1H2AA (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or p

Length: 396 Sequence: atgtctggac gagggaagca gggaggaaaa gcacgcgcca agtctaagtc tcgctcttct agagcgggtt tgcagtttcc cgtaggccgg atccatcgtc tgcttcgtaa gggaaactat gcagagcgga taggggcagg cgcaccagtg tatttggcgg cagtgttaga gtatctcaca gcagaaatcc ttgagctggc aggcaatgcg tctcgcgata acaaaaaaac tcgcattatt ccccgccacc tgcagctagc gatccgcaat gatgaggaac tcaataagct tttgggcggc gtgaccattg cccagggcgg agtcctgcct aacattcagg cagtgctgct gcccaagaag actgagagtc accaccataa agcccaaagc Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]