GUCA1A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 606 Sequence: atgggcaacg tgatggaggg aaagtcagtg gaggagctga gcagcaccga gtgccaccag tggtacaaga agttcatgac tgagtgcccc tctggccaac tcaccctcta tgagttccgc cagttcttcg gcctcaagaa cctgagcccg tcggccagcc agtacgtgga acagatgttt gagacttttg acttcaacaa ggacggctac attgatttca tggagtacgt ggcagcgctc agcttggtcc tcaaggggaa ggtggaacag aagctccgct ggtacttcaa gctctatgat gtagatggca acggctgcat tgaccgcgat gagctgctca ccatcatcca ggccattcgc gccattaacc cctgcagcga taccaccatg actgcagagg agttcaccga tacagtgttc tccaagattg acgtcaacgg ggatggggaa ctctccctgg aagagtttat agagggcgtc cagaaggacc agatgctcct ggacacactg acacgaagcc tggaccttac ccgcatcgtg cgcaggctcc agaatggcga gcaagacgag gagggggctg acgaggccgc tgaggcagcc Protein function: Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated (PubMed:19459154, PubMed:30622141, PubMed:18706439, PubMed:30184081). This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light. [The UniProt Consortium]