GTF2H3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 927 Sequence: atggtttcag acgaagatga attgaatctt ctggttattg tagttgatgc caacccaatt tggtggggaa agcaagcatt aaaggaatct cagttcactt tatccaaatg catagatgcc gtgatggtgc tgggaaattc gcatttattc atgaatcgtt ccaacaaact tgctgtgata gcaagtcaca ttcaagaaag ccgattctta tatcctggaa agaatggcag acttggagac ttcttcggag accctggcaa ccctcctgaa tttaatccct ctgggagtaa agatggaaaa tacgaacttt taacctcagc aaatgaagtt attgttgaag agattaaaga tctaatgacc aaaagtgaca taaagggtca acatacagaa actttgctgg caggatccct ggccaaagcc ctttgctaca ttcatagaat gaacaaggaa gttaaagaca atcaggaaat gaaatcaagg atattggtga ttaaggctgc agaagacagt gcgttgcagt atatgaactt catgaatgtc atctttgcag cacagaaaca gaatattttg attgatgcct gtgttttaga ctccgactca gggctcctcc aacaggcttg tgacatcacg ggaggactgt acctgaaggt gcctcagatg ccttctcttc tgcagtattt gctgtgggtg tttcttcccg atcaagatca gagatctcag ttaatcctcc cacccccggt tcatgttgac tacagggctg cttgcttctg tcatcgaaat ctcattgaaa ttggttatgt ctgttctgtg tgtttgtcaa tattctgcaa tttcagcccc atttgtacta cgtgcgagac agcctttaaa atttctctgc ctccagtgct gaaagccaag aaaaagaaac tgaaagtgtc Protein function: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. [The UniProt Consortium]