GPR68 (Vector pUC, Accession No. BC096071)

Length: 1128 Sequence: ATGAGGAGTG TGGCCCCTTC AGGCCCAAAG ATGGGGAACA TCACTGCAGA CAACTCCTCG ATGAGCTGTA CCATCGACCA TACCATCCAC CAGACGCTGG CCCCGGTGGT CTATGTTACC GTGCTGGTGG TGGGCTTCCC GGCCAACTGC CTGTCCCTCT ACTTCGGCTA CCTGCAGATC AAGGCCCGGA ACGAGCTGGG CGTGTACCTG TGCAACCTGA CGGTGGCCGA CCTCTTCTAC ATCTGCTCGC TGCCCTTCTG GCTGCAGTAC GTGCTGCAGC ACGACAACTG GTCTCACGGC GACCTGTCCT GCCAGGTGTG CGGCATCCTC CTGTACGAGA ACATCTACAT CAGCGTGGGC TTCCTCTGCT GCATCTCCGT GGACCGCTAC CTGGCTGTGG CCCATCCCTT CCGCTTCCAC CAGTTCCGGA CCCTGAAGGC GGCCGTCGGC GTCAGCGTGG TCATCTGGGC CAAGGAGCTG CTGACCAGCA TCTACTTCCT GATGCACGAG GAGGTCATCG AGGACGAGAA CCAGCACCGC GTGTGCTTTG AGCACTACCC CATCCAGGCA TGGCAGCGCG CCATCAACTA CTACCGCTTC CTGGTGGGCT TCCTCTTCCC CATCTGCCTG CTGCTGGCGT CCTACCAGGG CATCCTGCGC GCCGTGCGCC GGAGCCACGG CACCCAGAAG AGCCGCAAGG ACCAGATCCA GCGGCTGGTG CTCAGCACCG TGGTCATCTT CCTGGCCTGC TTCCTGCCCT ACCACGTGTT GCTGCTGGTG CGCAGCGTCT GGGAGGCCAG CTGCGACTTC GCCAAGGGCG TTTTCAACGC CTACCACTTC TCCCTCCTGC TCACCAGCTT CAACTGCGTC GCCGACCCCG TGCTCTACTG CTTCGTCAGC GAGACCACCC ACCGGGACCT GGCCCGCCTC CGCGGGGCCT GCCTGGCCTT CCTCACCTGC TCCAGGACCG GCCGGGCCAG GGAGGCCTAC CCGCTGGGTG CCCCCGAGGC CTCCGGGAAA AGCGGGGCCC AGGGTGAGGA GCCCGAGCTG TTGACCAAGC TCCACCCGGC CTTCCAGACC CCTAACTCGC CAGGGTCGGG CGGGTTCCCC ACGGGCAGGT Protein function: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer. [The UniProt Consortium]