GNL3L (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1749 Sequence: atgatgaaac ttagacacaa aaataaaaag ccaggtgaag gttccaaggg ccacaagaag ataagttggc cctaccctca gcctgcaaag caaaatggga agaaagcaac ctccaaagtg ccctctgcac ctcattttgt tcaccccaat gatcatgcca atcgagaggc tgaattaaag aagaagtggg ttgaggagat gagggagaag cagcaagccg cccgggagca agaaagacaa aaacgcagga ccattgagag ctactgtcag gatgtcctaa gacgccagga ggagtttgag cataaggagg aagttttgca ggaattaaat atgtttcctc agctggatga cgaggccacg aggaaggctt attacaagga gttccgtaag gtggtggaat actctgatgt gattctggaa gtcctggatg ccagagaccc attaggctgc cgctgcttcc aaatggagga ggctgtcctg cgagcacaag gcaacaagaa gctggtcctg gtcttgaaca agattgacct ggtccccaag gaggttgtgg agaaatggct ggattacctt cggaatgagt tgccaaccgt ggctttcaag gccagtaccc agcatcaggt caaaaacctg aatcgttgca gtgtgccagt agatcaggcc tctgagtcac tgctgaaaag caaagcctgc tttggagctg aaaacctcat gagggttctg gggaactatt gccgccttgg tgaagtgcgc acccacattc gtgtgggtgt tgtgggtctt cccaatgttg ggaagagcag cctgatcaat agcctgaagc gcagccgcgc atgcagcgtg ggagctgttc ctggaattac caaattcatg caggaggtct acctggacaa gttcatccgg ctcttggatg ctccaggcat tgtcccaggg cccaactcag aggtgggcac catcctgcgt aactgcgtcc acgtgcagaa gctggcagac cctgtgaccc cagtggagac catcctgcag cgctgcaacc tggaggagat ttccaactat tatggcgtct ctgggttcca gaccactgag cactttctga cggcagtggc ccaccgtttg gggaagaaga agaagggagg cttatatagt caggaacagg cggccaaagc tgtcctagct gactgggtga gcgggaagat cagcttctat ataccaccac cagccactca cactctgccc acccatctca gtgctgagat cgttaaggaa atgaccgagg tctttgacat cgaggatact gagcaggcca atgaagacac catggaatgc ttggccaccg gagaatctga tgagctgttg ggtgacacgg acccacttga aatggagatc aagttgctcc attctccgat gacgaaaata gcagatgcca ttgaaaataa aaccaccgtg tataagattg gagatctcac tgggtattgc accaatccga accgtcatca gatggggtgg gctaaacgca atgtggacca ccgccctaag agcaacagta tggtggatgt ctgctcagtg gaccgccgct cagtgctgca gaggatcatg gagacggacc ccctgcaaca gggccaggct ctggcatctg ccctgaaaaa taagaagaag atgcagaaac gtgcagataa aatcgccagc aagctgtctg attccatgat gtctgctctc gacctctctg gcaatgctga tgatggtgtt Protein function: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. [The UniProt Consortium]