GGA1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 270 Sequence: atggagcccg cgatggagcc ggagactctg gaggcgcgaa tcaatagagc cacgaacccc ctgaacaagg agctcgactg ggccagcatc aacggcttct gcgagcagct caacgaggac tttgaggggc ctccactcgc cacccggctg ctggcccaca agatccagtc cccacaggag tgggaggcga tccaggcctt gacggtgaga aggggagagg ccaccatccg tcccccgcca tgtgacgaca ccaagggagg Protein function: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif (PubMed:11301005, PubMed:15886016). Mediates export of the GPCR receptor ADRA2B to the cell surface (PubMed:27901063). Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network (PubMed:15886016, PubMed:15615712). [The UniProt Consortium]