FUT2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1032 Sequence: ATGCTGGTCG TTCAGATGCC TTTCTCCTTT CCCATGGCCC ACTTCATCCT CTTTGTCTTT ACGGTTTCCA CTATATTTCA CGTTCAGCAG CGGCTAGCGA AGATTCAAGC CATGTGGGAG TTACCGGTGC AGATACCAGT GCTAGCCTCA ACATCAAAGG CACTGGGACC CAGCCAGCTC AGGGGGATGT GGACGATCAA TGCAATAGGC CGCCTGGGGA ACCAGATGGG CGAGTACGCC ACACTGTACG CCCTGGCCAA GATGAACGGG CGGCCCGCCT TCATCCCGGC CCAGATGCAC AGCACCCTGG CCCCCATCTT CAGAATCACC CTGCCGGTGC TGCACAGCGC CACGGCCAGC AGGATCCCCT GGCAGAACTA CCACCTGAAT GACTGGATGG AGGAGGAATA CCGCCACTTC CCTGGGGAGT ACGTCCGCTT CACCGGCTAC CCCTGCTCCT GGACCTTCTA CCACCACCTC CGCCAGGAGA TCCTCCAGGA GTTCACCCTG CACGACCACG TGCGGGAGGA GGCCCAGAAG TTCCTGCGGG GCCTGCAGGT GAACGGGAGC CGGCCGGGCA CCTTTGTAGG GGTCCATGTT CGCCGAGGGG ACTATGTCCA TGTCATGCCA AAAGTGTGGA AGGGGGTGGT GGCCGACCGG CGATACCTAC AGCAGGCCCT GGACTGGTTC CGAGCTCGCT ACAGCTCCCT CATCTTCGTG GTCACCAGTA ATGGCATGGC CTGGTGTCGG GAGAACATTG ACACCTCCCA CGGTGATGTG GTGTTTGCTG GCGATGGCAT TGAGGGCTCA CCTGCCAAAG ATTTTGCTCT ACTCACACAG TGTAACCACA CCATCATGAC CATTGGGACG TTCGGGATCT GGGCCGCATA CCTCACGGGC GGAGACACCA TCTACCTGGC CAATTACACC CTCCCCGACT CCCCTTTCCT CAAAATCTTT AAGCCAGAGG CAGCCTTCCT GCCGGAGTGG ACAGGGATTG CCGCAGACCT GTCCCCCTTA CTCAAGCACT Protein function: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N- linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation (PubMed:7876235, PubMed:8018146, PubMed:12692541). Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition (PubMed:22068912, PubMed:21625510, PubMed:24733310). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:7876235). [The UniProt Consortium]