FERMT3 (Vector pUC, Accession No. BC004347)

Length: 1992 Sequence: atggcgggga tgaagacagc ctccggggac tacatcgact cgtcatggga gctgcgggtg tttgtgggag aggaggaccc agaggccgag tcggtcaccc tgcgggtcac tggggagtcg cacatcggcg gggtgctcct gaagattgtg gagcagatca atcgcaagca ggactggtca gaccatgcta tttggtggga acagaagagg cagtggctgc tgcagaccca ctggacactg gacaagtacg ggatcctggc cgacgcacgc ctcttctttg ggccccagca ccggcccgtc atccttcggt tgcccaaccg ccgcgcactg cgcctccgtg ccagcttctc ccagcccctc ttccaggctg tggctgccat ctgccgcctc ctcagcatcc ggcaccccga ggagctgtcc ctgctccggg ctcctgagaa gaaggagaag aagaagaaag agaaggagcc agaggaagag ctctatgact tgagcaaggt tgtcttggct gggggcgtgg cacctgcact gttccggggg atgccagctc acttctcgga cagcgcccag actgaggcct gctaccacat gctgagccgg ccccagccgc cacccgaccc cctcctgctc cagcgtctgc cacggcccag ctccctgtca gacaagaccc agctccacag caggtggctg gactcgtcgc ggtgtctcat gcagcagggc atcaaggctg gggacgcact ctggctgcgc ttcaagtact acagcttctt cgatttggat cccaagacag accccgtgcg gctgacacag ctgtatgagc aggcccggtg ggacctgctg ctggaggaga ttgactgcac cgaggaggag atgatggtgt ttgccgccct gcagtaccac atcaacaagc tgtcccagag cggggaggtg ggggagccgg ctggcacaga cccagggctg gacgacctgg atgtggccct gagcaacctg gaggtgaagc tggaggggtc ggcgcccaca gatgtgctgg acagcctcac caccatccca gagctcaagg accatctccg aatctttcgg ccccggaagc tgaccctgaa gggctaccgc caacactggg tggtgttcaa ggagaccaca ctgtcctact acaagagcca ggacgaggcc cctggggacc ccattcagca gctcaacctc aagggctgtg aggtggttcc cgatgttaac gtctccggcc agaagttctg cattaaactc ctagtgccct cccctgaggg catgagtgag atctacctgc ggtgccagga tgagcagcag tatgcccgct ggatggctgg ctgccgcctg gcctccaaag gccgcaccat ggccgacagc agctacacca gcgaggtgca ggccatcctg gccttcctca gcctgcagcg cacgggcagt gggggcccgg gcaaccaccc ccacggccct gatgcctctg ccgagggcct caacccctac ggcctcgttg ccccccgttt ccagcgaaag ttcaaggcca agcagctcac cccacggatc ctggaagccc accagaatgt ggcccagttg tcgctggcag aggcccagct gcgcttcatc caggcctggc agtccctgcc cgacttcggc atctcctatg tcatggtcag gttcaagggc agcaggaaag acgagatcct gggcatcgcc aacaaccgac tgatccgcat cgacttggcc gtgggcgacg tggtcaagac ctggcgtttc agcaacatgc gccagtggaa tgtcaactgg gacatccggc aggtggccat cgagtttgat gaacacatca atgtggcctt cagctgcgtg tctgccagct gccgaattgt acacgagtat atcgggggct acattttcct gtcgacgcgg gagcgggccc gtggggagga gctggatgaa gacctcttcc tgcagctcac cgggggccat gaggccttct Protein function: Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs). [The UniProt Consortium]