FBXO22 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1212 Sequence: atggagccgg taggctgctg cggcgagtgc cgcggctcct ccgtagaccc gcggagcacc ttcgtgttga gtaacctggc ggaggtggtg gagcgtgtgc tcaccttcct gcccgccaag gcgttgctgc gggtggcctg cgtgtgccgc ttatggaggg agtgtgtgcg cagagtattg cggacccatc ggagcgtaac ctggatctcc gcaggcctgg cggaggccgg ccacctggag gggcattgct tggttcgcgt ggtagcagag gagcttgaga atgttcgcat cttaccacat acagttcttt acatggctga ttcagaaact ttcattagtc tggaagagtg tcgtggccat aagagagcaa ggaaaagaac tagtatggaa acagcacttg cccttgagaa gctattcccc aaacaatgcc aagtccttgg gattgtgacc ccaggaattg tagtgactcc aatgggatca ggtagcaatc gacctcagga aatagaaatt ggagaatctg gttttgcttt attattccct caaattgaag gaataaaaat acaacccttt cattttatta aggatccaaa gaatttaaca ttagaaagac atcaactcac tgaagtaggt cttttagata accctgaact tcgtgtggtc cttgtctttg gttataattg ctgtaaggtg ggagccagta attatctgca gcaagtagtc agcactttca gtgatatgaa tatcatcttg gctggaggcc aggtggacaa cctgtcatca ctgacttctg aaaagaaccc tctggatatt gatgcctcgg gtgtggttgg actgtcattt agtggacacc gaatccagag tgccactgtg ctcctcaacg aggacgtcag tgatgagaag actgctgagg ctgcgatgca gcgcctcaaa gcggccaaca ttccagagca taacaccatt ggcttcatgt ttgcatgcgt tggcaggggc tttcagtatt acagagccaa ggggaatgtt gaggctgatg catttagaaa gttttttcct agtgttccct tattcggctt ctttggaaat ggagaaattg gatgtgatcg gatagtcact gggaacttta tattgaggaa atgtaatgag gtaaaagatg atgatctgtt tcatagctat acaacaataa tggcactcat acatctgggg tcatctaaat Protein function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome- dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function. [The UniProt Consortium]