FBXL5 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2076 Sequence: atggcgccct ttcctgaaga agtggacgtc ttcaccgccc cacactggcg gatgaagcag ctggtggggc tctactgcga caagctttct aaaaccaatt tttccaacaa caacgatttc cgtgctcttc tgcagtcttt gtatgctact ttcacggagt tcaaaatgca tgagcagatt gaaaatgaat acattattgg tttgcttcaa caacgcagcc agaccattta taatgtacat tctgacaata aactctccga gatgcttagc ctctttgaaa agggactgaa gaatgttaag aatgaatatg aacagttaaa ttatgcaaaa caactgaaag agagattgga ggcttttaca agagattttc ttcctcacat gaaagaggaa gaggaggttt ttcagcccat gttaatggaa tattttacct atgaagagct taaggatatt aaaaagaaag tgattgcaca acactgctct cagaaggata ctgcagaact ccttagaggt cttagcctat ggaatcatgc tgaagagcga cagaagtttt ttaaatattc cgtggatgaa aagtcagata aagaagcaga agtgtcagaa cactccacag gtataaccca tcttcctcct gaggtaatgc tgtcaatttt cagctatctt aatcctcaag agttatgtcg atgcagtcaa gtaagcatga aatggtctca gctgacaaaa acgagatcgc tttggaaaca tctttaccct gttcattggg ccagaggtga ctggtatagt ggtcccgcaa ctgaacttga tactgaacct gatgatgaat gggtgaaaaa taggaaagat gaaagtcgtg cttttcatga gtgggatgaa gatgctgaca ttgatgaatc tgaagagtct gcggaggaat caattgctat cagcattgca caaatggaaa aacgtttact ccatggctta attcataacg ttctaccata tgttggtact tctgtaaaaa ccttagtatt agcatacagc tctgcagttt ccagcaaaat ggttaggcag attttagagc tttgtcctaa cctggagcat ctggatctta cccagactga catttcagat tctgcatttg acagttggtc ttggcttggt tgctgccaga gtcttcggca tcttgatctg tctggttgtg agaaaatcac agatgtggcc ctagagaaga tttccagagc tcttggaatt ctgacatctc atcaaagtgg ctttttgaaa acatctacaa gcaaaattac ttcaactgcg tggaaaaata aagacattac catgcagtcc accaagcagt atgcctgttt gcacgattta actaacaagg gcattggaga agaaatagat aatgaacacc cctggactaa gcctgtttct tctgagaatt tcacttctcc ttatgtgtgg atgttagatg ctgaagattt ggctgatatt gaagatactg tggaatggag acatagaaat gttgaaagtc tttgtgtaat ggaaacagca tccaacttta gttgttccac ctctggttgt tttagtaagg acattgttgg actaaggact agtgtctgtt ggcagcagca ttgtgcttct ccagcctttg cgtattgtgg tcactcattt tgttgtacag gaacagcttt aagaactatg tcatcactcc cagaatcttc tgcaatgtgt agaaaagcag caaggactag attgcctagg ggaaaagact taatttactt tgggagtgaa aaatctgatc aagagactgg acgtgtactt ctgtttctca gtttatctgg atgttatcag atcacagacc atggtctcag ggttttgact ctgggaggag ggctgcctta tttggagcac cttaatctct ctggttgtct tactataact ggtgcaggcc tgcaggattt ggtttcagca tgtccttctc tgaatgatga atacttttac tactgtgaca acattaacgg tcctcatgct gataccgcca gtggatgcca gaatttgcag tgtggttttc gagcctgctg ccgctctggc Protein function: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued. [The UniProt Consortium]