FAM45A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1074 Sequence: atggctgcgg ccgaggtggc ggacactcag ctgatgcttg gagtcgggct gatcgaaaag gacacaaatg gagaagttct gtgggtgtgg tgttatcctt ccacgacagc cacattaagg aacctgctgc tgagaaaatg ctgccttaca gatgaaaaca aacttctcca tccctttgtc tttggtcagt acagaagaac atggttttat atcacaacaa ttgaagttcc agattcttcc attttgaaaa aggtgactca tttttctatt gtcctgaccg ccaaagattt taacccagag aagtatgctg ccttcactag gatattgtgt agaatgtacc tgaaacatgg gagcccagtt aaaatgatgg agagttatat tgcagttctc acaaagggga tatgccagag tgaagaaaac ggctctttcc ttagtaagga ttttgatgcc cgaaaggcct acctggctgg ctccatcaaa gacattgtat ctcagtttgg aatggaaact gttatcttac acacagcact gatgctaaag aaaagaattg tggtgtatca ccccaagata gaagcggtcc aggagttcac caggactctg cctgccctgg tgtggcaccg acaggactgg accatccttc actcttacgt gcacctcaac gccgatgagc tggaagccct gcagatgtgc acaggttacg tcgctggatt tgtagacttg gaggtgagca acagaccaga cctctatgat gtgtttgtga atctggcaga gagtgagatt accattgctc cccttgcaaa agaggccatg gcaatgggca aactgcacaa agaaatgggt cagctaattg ttcagtctgc agaagatcca gagaaatcag agagccacgt tatacaggat attgctctaa aaacaagaga aatctttacc aacctagcac cattttcaga agtttcggct gatggagaaa agagagtcct taatttggag gcgctaaagc aaaaacgatt tccaccagca acagaaaact tcctttatca tctagcagca gccgaacaaa tgctgaaaat Protein function: Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B. Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP- bound form. [The UniProt Consortium]