FA2H (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 843 Sequence: atggagaacg agcctgtagc ccttgaggaa actcagaaga cagatcctgc tatggaacca cggttcaaag tggtggattg ggacaaggac ctggtggact ggcgaaagcc tctcctgtgg caggtgggcc acttgggaga gaagtacgat gagtgggttc accagccggt gaccaggccc atccgcctct tccactcaga cctcattgag ggcctctcta agactgtctg gtacagtgtc cccatcatct gggtgcccct ggtgctgtat ctcagctggt cctactaccg aacctttgcc cagggcaacg tccgactctt cacgtcattt acaacagagt acacggtggc agtgcccaag tccatgttcc ccgggctctt catgctgggg acattcctct ggagcctcat cgagtacctc atccaccgct tcctgttcca catgaagccc cccagcgaca gctattacct catcatgctg cacttcgtca tgcacggcca gcaccacaag gcacccttcg acggctcccg cctggtcttc ccccctgtgc cagcctccct ggtgatcggc gtcttctact tgtgcatgca gctcatcctg cccgaggcag tagggggcac tgtgtttgcg gggggcctcc tgggctacgt cctctatgac atgacccatt actacctgca ctttggctcg ccgcacaagg gctcctacct gtacagcctg aaggcccacc acgtcaagca ccactttgca catcagaagt caggatttgg tatcagcact aaattgtggg attactgttt ccacaccctc actccagaga aaccccacct gaagacgcag Protein function: Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis (PubMed:15337768, PubMed:15863841, PubMed:17355976, PubMed:22517924). FA2H is stereospecific for the production of (R)-2- hydroxy fatty acids (PubMed:22517924). Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier (PubMed:17355976). Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins. [The UniProt Consortium]