ETF1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1215 Sequence: atgatatcat tgatcattcc tcccaaagac cagatttcac gagtggcaaa aatgttagcg gatgagtttg gaactgcatc taacattaag tcacgagtaa accgcctttc agtcctggga gccattacat ctgtacaaca aagactcaaa ctttataaca aagtacctcc aaatggtctg gttgtatact gtggaacaat tgtaacagaa gaaggaaagg aaaagaaagt caacattgac tttgaacctt tcaaaccaat taatacgtca ttgtatttgt gtgacaacaa attccataca gaggctctta cagcactact ttcagatgat agcaagtttg gattcattgt aatagatggt agtggtgcac tttttggcac actccaagga aacacaagag aagtcctgca caaattcact gtggatctcc caaagaaaca cggtagagga ggtcagtcag ccttgcgttt tgcccgttta agaatggaaa agcgacataa ctatgttcgg aaagtagcag agactgctgt gcagctgttt atttctgggg acaaagtgaa tgtggctggt ctagttttag ctggatccgc tgactttaaa actgaactaa gtcaatctga tatgtttgat cagaggttac aatcaaaagt tttaaaatta gttgatatat cctatggtgg tgaaaatgga ttcaaccaag ctattgagtt atctactgaa gtcctctcca acgtgaaatt cattcaagag aagaaattaa taggacgata ctttgatgaa atcagccagg acacgggcaa gtactgtttt ggcgttgaag atacactaaa ggctttggaa atgggagctg tagaaattct aatagtctat gaaaatctgg atataatgag atatgttctt cattgccaag gcacagaaga ggagaaaatt ctctatctaa ctccagagca agaaaaggat aaatctcatt tcacagacaa agagaccgga caggaacatg agcttatcga gagcatgccc ctgttggaat ggtttgctaa caactataaa aaatttggag ctacgttgga aattgtcaca gataaatcac aagaagggtc tcagtttgtg aaaggatttg gtggaattgg aggtatcttg cggtaccgag tagatttcca gggaatggaa taccaaggag gagacgatga attttttgac cttgatgact Protein function: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (PubMed:7990965, PubMed:24486019). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes (PubMed:30682371). [The UniProt Consortium]