EMG1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 735 Sequence: atggccgcgc ccagtgatgg attcaagcct cgtgaacgaa gcggtgggga gcaggcacag gactgggatg ctctgccacc caagcggccc cgactagggg caggaaacaa gatcggaggc cgtaggctta ttgtggtgct ggaaggggcc agtctggaga cagtcaaggt agggaagaca tatgagctac tcaactgtga caagcacaag tctatattgt tgaagaatgg acgggaccct ggggaagcgc ggccagatat cacccaccag agtttgctga tgctgatgga tagtcccctg aaccgagctg gcttgctaca ggtttatatc catacacaga agaatgttct gattgaagtg aatccccaga cccgaattcc cagaaccttt gaccgctttt gtggcctcat ggttcaactt ttacacaagc tcagtgttcg agcagctgat ggcccccaga agcttttgaa ggtaattaag aatccagtat cagatcactt tccagttgga tgtatgaaag ttggcacttc tttttccatc ccggttgtca gtgatgtgcg tgagctggtg cccagcagtg atcctattgt ttttgtggta ggggcctttg cccatggcaa ggtcagtgtg gagtatacag agaagatggt gtccatcagt aactaccccc tttctgctgc cctcacctgt gcaaaactta ccacagcctt tgaggaagta tggggggtca Protein function: S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates pseudouridine at position 1248 (Psi1248) in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Is not able to methylate uridine at this position (PubMed:20047967). Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes. [The UniProt Consortium]