DUS2L (Vector pENTR223.1, Accession No. BC006527)

Length: 1482 Sequence: atgattttga atagcctctc tctgtgttac cataataagc taatcctggc cccaatggtt cgggtaggga ctcttccaat gaggctgctg gccctggatt atggagcgga cattgtttac tgtgaggagc tgatcgacct caagatgatt cagtgcaaga gagttgttaa tgaggtgctc agcacagtgg actttgtcgc ccctgatgat cgagttgtct tccgcacctg tgaaagagag cagaacaggg tggtcttcca gatggggact tcagacgcag agcgagccct tgctgtggcc aggcttgtag aaaatgatgt ggctggtatt gatgtcaaca tgggctgtcc aaaacaatat tccaccaagg gaggaatggg agctgccctg ctgtcagacc ctgacaagat tgagaagatc ctcagcactc ttgttaaagg gacacgcaga cctgtgacct gcaagattcg catcctgcca tcgctagaag ataccctgag ccttgtgaag cggatagaga ggactggcat tgctgccatc gcagttcatg ggaggaagcg ggaggagcga cctcagcatc ctgtcagctg tgaagtcatc aaagccattg ctgataccct ctccattcct gtcatagcca acggaggatc tcatgaccac atccaacagt attcggacat agaggacttt cgacaagcca cggcagcctc ttccgtgatg gtggcccgag cagccatgtg gaacccatct atcttcctca aggagggtct gcggcccctg gaggaggtca tgcagaaata catcagatac gcggtgcagt atgacaacca ctacaccaac accaagtact gcttgtgcca gatgctacga gaacagctgg agtcgcccca gggaaggttg ctccatgctg cccagtcttc ccgggaaatt tgtgaggcct ttggccttgg tgccttctat gaggagacca cacaggagct ggatgcccag caggccaggc tctcagccaa gacttcagag cagacagggg agccagctga agatacctct ggtgtcatta agatggctgt caagtttgac cggagagcat acccagccca gatcacccct aagatgtgcc tactagagtg gtgccggagg gagaagttgg cacagcctgt gtatgaaacg gttcaacgcc ctctagatcg cctgttctcc tctattgtca ccgttgctga acaaaagtat cagtctacct tgtgggacaa gtccaagaaa ctggcggagc aggctgcagc catcgtctgt ctgcggagcc agggcctccc tgagggtcgg ctgggtgagg agagcccttc cttgcacaag cgaaagaggg aggctcctga ccaagaccct gggggcccca gagctcagga gctagcacaa cctggggatc tgtgcaagaa gccctttgtg gccttgggaa gtggtgaaga aagccccctg gaaggctggt Protein function: Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704). Negatively regulates the activation of EIF2AK2/PKR (PubMed:18096616). [The UniProt Consortium]