DOCK2 (Vector pUC, Accession No. BC113457)

Length: 5493 Sequence: ATGGCCCCCT GGCGCAAAGC TGACAAGGAG CGGCACGGCG TGGCCATATA CAACTTCCAA GGCAGCGGAG CCCCCCAGCT CTCCCTGCAG ATCGGCGATG TGGTGCGAAT ACAGGAGACG TGTGGAGACT GGTATAGGGG ATACCTCATA AAGCACAAAA TGTTACAGGG CATTTTTCCT AAGTCATTTA TCCACATCAA GGAAGTGACA GTTGAGAAAA GAAGAAATAC TGAGAACATC ATTCCTGCAG AAATTCCTCT GGCACAAGAA GTGACAACGA CACTTTGGGA ATGGGGAAGC ATCTGGAAAC AACTCTATGT GGCCAGCAAA AAGGAGCGTT TTCTCCAGGT GCAGTCCATG ATGTACGATC TGATGGAGTG GAGGTCCCAG CTTCTCTCAG GAACCTTACC CAAGGATGAG CTGAAGGAAC TGAAGCAGAA AGTCACGTCC AAAATTGACT ATGGCAACAA AATCCTTGAG CTTGATTTGA TTGTTAGAGA TGAAGACGGA AATATCTTGG ACCCTGATAA TACCAGTGTC ATCAGCTTGT TCCATGCACA TGAGGAAGCA ACTGATAAAA TCACAGAGCG TATCAAAGAA GAAATGTCAA AAGACCAGCC AGATTATGCA ATGTATTCCC GGATCTCCTC ATCCCCCACC CATAGCCTCT ATGTGTTTGT GAGAAACTTT GTGTGCAGAA TTGGGGAAGA TGCTGAGCTC TTCATGTCTC TCTACGACCC CAACAAGCAA ACGGTCATAA GTGAGAACTA CCTAGTGCGA TGGGGCAGCC GGGGCTTCCC TAAGGAGATT GAGATGCTCA ACAATCTGAA GGTGGTCTTC ACGGATCTTG GAAACAAAGA CCTCAACAGG GATAAAATTT ACTTGATTTG TCAAATAGTC CGGGTCGGCA AGATGGATCT TAAGGATACT GGTGCAAAGA AGTGCACGCA GGGACTGAGG AGGCCCTTTG GGGTGGCAGT TATGGATATA ACAGACATCA TCAAGGGGAA AGCAGAGAGT GATGAAGAAA AGCAGCACTT CATTCCTTTT CACCCGGTTA CAGCTGAGAA TGACTTCCTA CACAGCCTGC TGGGCAAAGT CATAGCCTCC AAGGGGGACA GTGGAGGGCA AGGCCTCTGG GTGACCATGA AGATGCTGGT GGGTGACATC ATTCAGATTC GCAAGGACTA TCCACACCTG GTGGACAGGA CAACCGTGGT GGCCAGGAAG CTGGGATTCC CAGAGATCAT CATGCCAGGG GATGTCAGGA ACGACATCTA CATTACTCTC TTACAAGGTG ACTTTGACAA GTACAACAAG ACCACACAGA GGAATGTGGA AGTCATCATG TGTGTGTGCG CGGAGGATGG CAAGACGCTG CCTAATGCAA TTTGCGTGGG AGCAGGGGAC AAGCCCATGA ATGAGTATCG CTCCGTTGTG TACTATCAAG TCAAACAGCC ACGCTGGATG GAAACAGTCA AGGTGGCTGT CCCTATTGAA GACATGCAGA GGATCCATCT GCGATTCATG TTTCGACATC GGTCATCTCT GGAATCTAAA GATAAAGGAG AAAAGAACTT TGCCATGTCC TATGTGAAGC TGATGAAAGA AGATGGGACT ACTCTACACG ATGGATTCCA TGACTTAGTT GTCCTCAAGG GGGACAGCAA GAAGATGGAG GATGCCAGCG CATACCTGAC CCTTCCTTCT TATCGACACC ATGTGGAAAA CAAGGGGGCC ACGCTGAGCA GGAGCTCCAG CAGTGTTGGG GGGCTTTCTG TCAGCTCCCG GGATGTGTTC TCCATTTCCA CCCTGGTGTG CTCCACAAAG CTCACTCAGA ATGTGGGCTT GCTGGGTTTG CTGAAGTGGC GTATGAAGCC TCAACTGCTA CAGGAGAATT TAGAAAAGTT GAAGATTGTG GATGGAGAGG AAGTGGTGAA GTTTCTCCAG GATACTCTGG ATGCCCTCTT CAACATCATG ATGGAGCATT CTCAAAGTGA TGAATATGAC ATCCTCGTCT TTGATGCCTT GATTTACATA ATAGGACTCA TTGCAGACCG GAAATTTCAG CATTTCAACA CCGTTCTGGA GGCTTACATC CAACAGCATT TCAGTGCGAC CTTGGCTTAC AAGAAATTGA TGACAGTGCT GAAGACTTAC TTGGATACCT CCAGCAGAGG GGAGCAATGT GAGCCAATCC TAAGAACGCT GAAGGCTTTG GAATATGTGT TCAAGTTCAT TGTTCGGTCG AGGACATTAT TTTCACAGCT TTATGAAGGC AAAGAACAGA TGGAGTTTGA AGAATCCATG AGACGGCTCT TTGAATCCAT CAACAATCTG ATGAAAAGTC AATACAAAAC TACCATCCTT TTGCAGGTGG CGGCTTTGAA ATACATCCCA TCTGTCCTGC ATGATGTAGA AATGGTCTTT GATGCGAAGT TACTCAGCCA ACTCCTGTAT GAGTTCTACA CCTGCATCCC TCCTGTGAAA CTCCAGAAGC AGAAAGTACA GTCTATGAAT GAGATAGTCC AGAGCAACCT CTTTAAAAAG CAAGAATGCC GGGACATTCT GCTTCCTGTC ATCACCAAAG AGCTGAAGGA GCTGCTGGAG CAGAAGGATG ACATGCAACA CCAGGTCCTG GAGAGGAAGT ACTGCGTTGA ATTGCTCAAC AGCATCTTGG AAGTCCTTAG CTACCAGGAT GCGGCCTTCA CCTACCACCA TATCCAAGAG ATCATGGTCC AGCTGCTGCG GACAGTGAAC CGGACAGTCA TCACCATGGG CCGGGATCAC ATTCTGATTA GTCACTTTGT GGCATGTATG ACAGCCATCT TAAACCAGAT GGGTGACCAG CACTACTCCT TCTACATTGA GACCTTCCAG ACCAGCTCTG AACTTGTGGA CTTCTTGATG GAGACCTTCA TCATGTTCAA GGACCTCATT GGAAAGAACG TGTACCCTGG AGACTGGATG GCCATGAGCA TGGTTCAAAA CAGGGTCTTC CTGAGAGCTA TCAACAAGTT TGCAGAAACC ATGAACCAGA AGTTCCTAGA ACACACGAAC TTTGAGTTCC AGCTGTGGAA CAACTATTTT CATCTGGCAG TGGCTTTTAT CACCCAGGAT TCTCTGCAGC TGGAGCAGTT CTCACACGCC AAATACAACA AAATCCTGAA TAAGTATGGG GACATGAGAC GGCTAATTGG CTTCTCCATC CGTGATATGT GGTACAAGCT TGGTCAGAAC AAAATCTGCT TCATCCCAGG CATGGTAGGA CCTATATTAG AGATGACACT TATCCCTGAG GCTGAGCTCC GGAAAGCCAC CATACCAATC TTCTTCGACA TGATGCTGTG TGAATATCAA AGAAGTGGGG ATTTCAAAAA GTTTGAAAAC GAAATCATCC TGAAGCTGGA CCACGAGGTA GAAGGGGGCC GAGGCGACGA GCAGTACATG CAGCTGCTGG AGTCAATCCT GATGGAATGT GCTGCAGAGC ACCCAACCAT TGCCAAGTCG GTGGAGAACT TCGTGAACCT GGTCAAAGGC CTCCTGGAGA AGCTGCTGGA TTACCGGGGT GTGATGACAG ATGAGAGCAA AGACAACCGC ATGAGCTGCA CCGTGAACCT GCTGAATTTC TACAAAGATA ACAACAGGGA GGAGATGTAC ATAAGGTACC TGTACAAACT CCGCGATCTT CACCTGGACT GTGACAATTA CACAGAGGCT GCCTACACGC TCCTTCTCCA CACCTGGCTT CTCAAGTGGT CGGATGAGCA GTGTGCATCA CAGGTCATGC AGACAGGCCA GCAGCACCCC CAGACACACC GGCAGCTCAA GGAGACGCTC TACGAGACCA TCATAGGCTA CTTTGACAAA GGAAAGATGT GGGAAGAGGC CATAAGTCTG TGCAAGGAGC TGGCGGAACA GTACGAGATG GAGATCTTTG ACTATGAGCT GCTCAGCCAG AACCTGATCC AGCAGGCAAA ATTCTATGAA AGCATCATGA AAATCCTCAG GCCCAAACCA GACTACTTTG CTGTTGGATA CTACGGCCAG GGATTCCCCT CCTTCCTGCG GAACAAAGTG TTCATCTACC GCGGGAAGGA ATATGAGCGA AGAGAAGATT TCCAGATGCA GCTGATGACC CAGTTCCCCA ATGCAGAGAA GATGAACACC ACCTCTGCCC CGGGAGATGA TGTGAAGAAT GCCCCAGGCC AGTATATCCA GTGCTTCACT GTCCAGCCTG TCTTGGATGA ACATCCCAGG TTCAAGAATA AGCCAGTGCC TGACCAGATT ATAAACTTCT ACAAATCCAA CTACGTGCAA AGGTTCCACT ACTCCCGGCC CGTGCGCAGG GGGACCGTAG ACCCAGAGAA TGAGTTTGCT TCCATGTGGA TTGAGAGAAC CTCCTTCGTG ACTGCATACA AGCTGCCGGG GATCCTGCGC TGGTTTGAGG TGGTGCACAT GTCGCAGACC ACAATTAGTC CTCTGGAGAA TGCCATAGAA ACCATGTCCA CGGCCAATGA GAAGATCCTG ATGATGATAA ACCAGTACCA GAGTGATGAG ACCCTCCCCA TCAACCCACT CTCCATGCTC CTGAACGGGA TTGTGGACCC TGCTGTCATG GGAGGCTTCG CCAAGTATGA GAAGGCCTTC TTCACTGAAG AGTATGTCAG GGACCACCCT GAGGACCAGG ACAAGCTGAC CCACCTCAAG GACCTGATTG CATGGCAGAT CCCCTTCTTG GGAGCTGGGA TTAAGATCCA TGAGAAAAGG GTGTCAGATA ACTTGCGACC CTTCCATGAC CGGATGGAGG AATGTTTCAA GAACCTGAAA ATGAAGGTGG AGAAGGAGTA CGGTGTCCGA GAGATGCCTG ACTTTGACGA CAGGAGAGTG GGCCGTCCCA GGTCTATGCT GCGCTCATAC AGACAGATGT CCATCATCTC TCTGGCTTCC ATGAATTCTG ACTGCAGCAC CCCCAGCAAG CCTACCTCAG AGAGCTTTGA CCTGGAATTA GCATCACCCA AGACGCCGAG AGTGGAGCAG GAGGAACCGA TCTCCCCGGG GAGCACCCTG CCTGAGGTCA AGCTGCGGAG GTCCAAGAAG AGGACAAAGA GAAGCAGCGT AGTTTTTGCG GATGAGAAAG CAGCTGCAGA GTCGGACCTG AAGCGGCTTT CCAGGAAGCA TGAGTTCATG AGTGACACCA ACCTCTCGGA GCATGCGGCC ATCCCCCTCA AGGCGTCTGT CCTCTCTCAA ATGAGCTTTG CCAGCCAGTC CATGCCTACC ATCCCAGCCC TGGCGCTCTC AGTGGCAGGC ATCCCTGGGT TGGATGAGGC CAACACATCT CCCCGCCTCA GCCAGACCTT CCTCCAACTC TCAGATGGTG ACAAGAAGAC ACTCACACGG AAGAAGGTCA ATCAGTTCTT CAAGACAATG CTGGCCAGCA AATCGGCTGA AGAAGGCAAA CAGATCCCAG ACTCGCTGTC CACGGACCTG Protein function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. [The UniProt Consortium]