DNMBP (Vector pUC, Accession No. BC041628)

Length: 2472 Sequence: atgacgctcc tctcctccca gtcttcatca ctggtggccc cttctgggtc tgtgtctgcc gaaaatccag agcagaggat gctggagaag agagccaagg tcatagaaga acttcttcag acagaaagag actacattcg ggatctggaa atgtgtattg agcggatcat ggtacccatg cagcaggcac aggtaccaaa cattgatttt gagggacttt ttggaaatac gcagatggtg attaaggtct caaagcaatt attggctgct ctggaaatca gcgatgctgt aggacctgtg tttcttggtc accgggatga gcttgaggga acatacaaga tttactgcca gaatcatgat gaggccattg cgctgcttga aatctacgag aaggatgaga agatccagaa gcatcttcag gactccttgg cagatctgaa gagcctatac aacgaatggg gatgcacaaa ttatattaac ctgggctcct tcctcatcaa accagtacag agagtaatgc gttacccgct gttgctaatg gagttgctga attccacccc agaatcccac ccagataaag tgcctttaac caatgcagtc cttgcggtca aggaaatcaa tgttaacatt aatgaatata aacggcgaaa ggacctggtc ctcaagtacc gtaagggtga tgaagatagc cttatggaga aaatttccaa actgaacatc cactccatca tcaagaaatc caaccgagtt agcagtcacc tgaagcatct cactggcttt gctcctcaga taaaagatga agtatttgaa gaaacagaaa aaaacttccg aatgcaagaa agattgatta agtcttttat ccgagacctg tctctctacc tccagcacat ccgggagtcc gcatgtgtga aagtggtggc tgctgtgagc atgtgggatg tgtgcatgga gagaggacac cgggacctgg agcagtttga gagggtgcat cgctacatca gtgaccagct cttcacaaac tttaaggaga ggacagagcg gcttgtcatc tcccccttaa atcagttact gagcatgttt acagggcccc ataagctggt acagaaacgc tttgacaagc tcctggactt ctataactgt acagaacggg cagaaaagct aaaggacaag aagaccctgg aggagctgca gtcggcccgg aacaactatg aggccctgaa tgcacagctg ctggatgagc tgcccaagtt ccaccagtac gcccagggcc tcttcaccaa ctgtgtccac ggctatgctg aagcccactg tgactttgtg caccaggctc tggagcaatt aaagccactg ctttcgttac tcaaagtggc tggcagagag ggaaacctta ttgccatctt ccacgaagag cacagcagag ttctgcagca actccaggtt tttaccttct tcccggagtc tcttccagct accaagaagc cgtttgagag gaaaaccatt gaccgccagt ctgctcgaaa gccactcctg ggcctgccaa gttacatgct acagtcagaa gaactccggg cctccctcct ggccaggtat ccccctgaaa aactcttcca ggcagaacgg aacttcaatg ctgctcaaga cttggatgtc tcacttttgg aaggtgacct ggtgggtgtg attaagaaaa aagaccccat gggcagccag aaccgctggc tgattgacaa tggagtcacc aaaggcttcg tgtacagctc tttcctaaag ccctacaatc ctcgccgcag ccactccgat gcctccgtgg gtagccactc ctccacagag tctgagcacg gcagctcctc ccccaggttc ccacgccaga acagcggcag caccctgacc ttcaacccca gcagcatggc tgtatccttt acctcggggt cttgccagaa gcagcctcaa gatgcatctc ctccgccaaa agaatgggac caaggaactc tcagtgcatc cctaaatccg agtaattcag agagtagtcc ttccagatgc ccttcagacc cagactctac ctcccagcca aggtcagggg actctgcaga tgtagctaga gatgtaaagc aacccactgc cacgccgagg agctaccgga acttcaggca tccagaaata gttggctact ccgtaccagg acgaaatggg caaagtcaag acctcgtcaa aggatgtgca agaacagccc aggctccgga agacagaagt acagagccag atggcagtga ggcagaaggc aaccaggtct attttgctgt ctacaccttc aaggcacgaa acccaaatga gctgagcgtg tcagccaatc agaaactcaa gatcctcgag tttaaagatg ttacaggaaa tacagagtgg tggttagctg aggttaacgg gaagaagggc tacgttccct ccaattatat ccgcaaaacc gagtacacct Protein function: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:19767742, PubMed:17015620). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. [The UniProt Consortium]