DND1 (Vector pUC, Accession No. BC033496)

Length: 1062 Sequence: atgcagtcca agcgggattg tgagctgtgg tgtgagaggg tgaatccaga gaacaaggcg gcgctggagg cgtgggtcag ggagacaggc atccgcctgg tgcaggtgaa cgggcagagg aagtatggcg ggccaccccc aggctgggtg ggcagcccgc cgccagctgg gtcagaggtg ttcatcgggc ggctgcctca ggacgtgtac gagcaccagc ttatcccgct gttccagcgc gtgggccgcc tctacgagtt ccgcctgatg atgaccttca gcggcctgaa ccgcggcttc gcctatgccc gctacagctc gaggcgcggc gcgcaggccg ccatcgccac gctgcacaac catccgctgc ggccgtcctg cccgctgctc gtgtgccgca gcaccgagaa gtgtgagctg agcgttgacg gcctgccgcc gaatctgacc cgcagcgcgc tgctgctcgc gctgcagccg ctgggtcccg gcttgcagga ggcgcggctg ctgcccagcc ccggaccggc gcccgggcag atcgctctgc tcaaattcag ctcgcaccgg gccgctgcca tggccaaaaa ggccctggtg gaagggcagt cacacctctg tggagagcag gtggctgtgg agtggctcaa gccagacctg aagcagcgac ttcgccagca gcttgtgggt cccttcttgc ggtccccaca gccagagggc agccagttgg ctttggcaag ggacaagtta gggttccaag gggctcgggc taccctgcag ttgctgtgcc aacgaatgaa gctgggcagc cctgtgttcc tcaccaagtg tttgggcata ggacctgctg gctggcaccg cttctggtac caggtggtga ttcctgggca tccggtgccc ttcagcggcc tcatctgggt tgtgctgacc ctagatggcc gggatgggca tgaggtggcc aaggatgctg tgtctgtacg gctgctgcag gcactcagtg agtctggggc caacctcctg tggtctgctg gggctgaggc aggtaccatg gttaaacagt Protein function: RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells. Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence- specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival. However, does not seem to be essential for PGC migration. [The UniProt Consortium]