DLX1 (Vector pUC, Accession No. BC036189)

Length: 708 Sequence: atggagtttg ggccgcccaa ccagcaaatg tctccttctc ccatgtccca cgggcactac tccatgcact gtttacactc ggcgggccat tcgcagcccg acggcgccta cagctcagcc tcgtccttct cccgaccgct gggctacccc tacgtcaact cggtcagcag ccacgcatcc agcccctaca tcagttcggt gcagtcctac ccgggcagcg ccagcctcgc ccagagccgc ctggaggacc caggggcgga ctcggagaag agcacggtgg tggaaggcgg tgaagtgcgc ttcaatggca agggaaaaaa gatccgtaaa cccaggacga tttattgcag tttgcagttg caggctttga accggaggtt ccagcaaact cagtacctag ctctgccgga gagggcggag ctcgcggcct ctttgggact cacacagact caggtcaaga tctggttcca aaacaagcga tccaagttca agaagctgat gaagcagggt ggggcggctc tggagggtag tgcgttggcc aacggtcggg ccctgtctgc tggctcccca cccgtgccgc ccggctggaa ccctaactct tcatccggga agggctcagg aggaaacgcg ggctcctata tccccagcta cacatcgtgg tacccttcag cgcaccaaga agctatgcag caaccccaac Protein function: Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. [The UniProt Consortium]