DENND1A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1680 Sequence: atgggctcca ggatcaagca gaatccagag accacatttg aagtatatgt tgaagtggcc tatcccagga caggtggcac tctttcagat cctgaggtgc agaggcaatt cccggaggac tacagtgacc aggaagttct acagactttg accaagtttt gtttcccctt ctatgtggac agcctcacag ttagccaagt tggccagaac ttcacattcg tgctcactga cattgacagc aaacagagat tcgggttctg ccgcttatct tcaggagcga agagctgctt ctgtatctta agctatctcc cctggttcga ggtattttat aagctgctta acatcctggc agattacacg acaaaaagac aggaaaatca gtggaatgag cttcttgaaa ctctgcacaa acttcccatc cctgacccag gagtgtctgt ccatctcagc gtgcattctt attttactgt gcctgatacc agagaacttc ccagcatacc tgagaataga aatctgacag aatattttgt ggctgtggat gttaacaaca tgttgcatct gtacgccagt atgctgtacg aacgccggat actcatcatt tgcagcaaac tcagcactct gactgcctgc atccacgggt ctgcggcgat gctctacccc atgtactggc agcacgtgta catccccgtg ctgccgccgc atctgctgga ctactgctgt gctcccatgc cctacctcat aggaatccat ttaagtttaa tggagaaagt cagaaacatg gccctggatg atgtcgtgat cctgaatgtg gacaccaaca ccctggaaac ccccttcgat gacctccaga gcctcccaaa cgacgtgatc tcttccctga agaacaggct gaaaaaggtc tccacaacca ctggggatgg tgtggccaga gcgttcctca aggcccaggc tgctttcttc ggtagctacc gaaacgctct gaaaatcgag ccggaggagc cgatcacttt ctgtgaggaa gccttcgtgt cccactaccg ctccggagcc atgaggcagt tcctgcagaa cgccacacag ctgcagctct tcaagcagtt tattgatggt cgattagatc ttctcaattc cggcgaaggt ttcagtgatg tttttgaaga ggaaatcaac atgggcgagt acgctggcag tgacaaactg taccatcagt ggctctccac tgtccggaaa ggaagtggag caattctgaa tactgtaaag accaaagcaa atccggccat gaagactgtc tacaagttcg caaaagatca tgcaaaaatg ggaataaaag aggtgaaaaa ccgcttgaag caaaaggaca ttgccgagaa tggctgcgcc cccaccccag aagagcagct gccaaagact gcaccgtccc cactggtgga ggccaaggac cccaagctcc gagaagaccg gcggccaatc acagtccact ttggacaggt gcgcccacct cgtccacatg ttgttaagag accaaagagc aacatcgcag tggaaggccg gaggacgtct gtgccgagcc ctgagcaaaa caccattgca acaccagcta cactccacat cctacagaaa agcattaccc attttgcggc caagttcccg acgagaggct ggacctcttc Protein function: Guanine nucleotide exchange factor (GEF) regulating clathrin- mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP- bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P. [The UniProt Consortium]