DDI1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

Length: 1191 Sequence: atgctgatca ccgtgtactg cgtgcggagg gacctctccg aggtcacctt ctctctccag gtcagccccg actttgagct ccgaaacttc aaggtcctct gcgaagcgga gtccagagtc cccgtcgaag agatccagat catccacatg gagcgactcc tcatcgagga ccactgttcc ctgggctcct acggcctcaa agatggcgat atcgtggttt tactgcagaa ggacaatgtg ggacctcggg ctccagggcg tgccccgaac cagcctcgtg tagacttcag tggcattgcg gtgcctggga cgtccagctc ccgtccacag caccctggac agcagcagca gcgcacaccc gctgcccagc ggtcacaggg cttggcgtca ggagagaagg tggccggcct gcaaggtctg ggcagccccg ccctgatccg cagcatgctg ctctccaacc cccacgatct gtccctgctc aaggaacgca accctccctt ggcggaagcc ctgctcagcg gaagccttga gaccttttct caggtgctga tggagcagca aagggaaaag gccttgagag agcaagagag gcttcgtctc tacacagccg acccactgga tcgggaagct caggccaaaa tagaagagga aatccggcag caaaacattg aagaaaacat gaatatagcg atagaagagg cccccgagag ttttggacaa gtgacgatgc tctacattaa ctgcaaagtg aatgggcatc ctttgaaggc ttttgttgac tcgggcgccc agatgaccat tatgagccag gcttgtgccg agcgatgtaa catcatgagg ctggtggacc gacggtgggc tggggttgct aaaggagtgg gcacacagag aattattggc cgtgttcatc tagctcagat tcaaattgaa ggtgatttct tacagtgctc tttctccata cttgaggatc aacccatgga tatgcttcta ggcctagata tgctccggag acatcaatgt tccatcgatt tgaagaaaaa tgtgctggtc atcggcacca ctggcacgca gacttatttt cttcctgagg gagagttgcc cttatgctct aggatggtaa gtgggcaaga tgagtcttcg gacaaggaaa ttacacattc agtcatggat tcaggacgaa aagaacatta Protein function: Probable aspartic protease (Probable). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable). Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (PubMed:29290612). [The UniProt Consortium]