DCPS (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A

DCPS (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CSB-CL836191HU.10 10 µg - - -

10 - 14 business days*

176.00€
 
Length: 1014 Sequence: atggcggacg cagctcctca actaggcaag aggaagcgcg aattggacgt ggaggaggcc... more
Product information "DCPS (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC, A"
Length: 1014 Sequence: atggcggacg cagctcctca actaggcaag aggaagcgcg aattggacgt ggaggaggcc cacgccgcca gcacagagga aaaggaggca ggagttggaa atggtacctg tgctcctgtc cgcttaccgt tctccggctt cagactgcag aaggtgctga gggagtctgc gcgggacaaa atcattttcc tacacgggaa ggtgaatgag gcctctgagg atggggatgg agaggatgcc gttgtgatcc tggagaagac gccatttcag gtggaacagg tggctcagct cctgacgggc agccctgagc tccaattgca gttctccaat gatatctaca gcacctatca cttgttccct ccaagacaac tgaatgatgt aaagacgacc gtggtttacc ctgccacaga gaaacacctg cagaagtacc tgcgccagga cctccgcctg atccgagaga cgggagatga ctacaggaac attactttac cccacctgga gtcccagagc ctcagcatcc agtgggtgta taacattctc gacaagaagg ctgaagcgga ccggattgtt ttcgagaacc cagatccctc tgatggtttt gtcctcatcc ctgacctcaa gtggaaccaa cagcagctcg atgacttgta cttgatcgcc atctgccatc gccggggcat cagatcccta cgcgacctta ctccggagca cttgccgctg ctcaggaaca tcctccacca ggggcaggag gccatcctgc agcgctaccg gatgaaggga gaccatctgc gagtatacct gcactacctg ccctcctact accacctgca tgtgcacttc accgccctgg gcttcgaggc ccccggctca ggcgtggagc gggcccacct gctggctgag gtgatcgaga acttggagtg tgaccctagg cactaccagc agcgcacgct caccttcgcc ctcagggctg acgaccccct gctcaagctc ttgcaggagg ctcagcaaag Protein function: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7- methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7- methylguanosine diphosphate (m7GDP) to m7GMP (PubMed:22985415). May also play a role in the 5'->3 mRNA decay pathway, m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP (PubMed:14523240). Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death. [The UniProt Consortium]
Keywords: DCPS, DCS1, DCS-1, HINT-5, HSPC015, EC=3.6.1.59, m7GpppX diphosphatase, Decapping scavenger enzyme, Histidine triad protein member 5, Scavenger mRNA-decapping enzyme DcpS, Hint-related 7meGMP-directed hydrolase
Supplier: Cusabio
Supplier-Nr: CL836191HU

Properties

Application: Molecular biology, clone
Species reactivity: human

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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