DBF4 (Vector pUC, Accession No. BC036045)

Length: 2025 Sequence: atgaactccg gagccatgag gatccacagt aaaggacatt tccagggtgg aatccaagtc aaaaatgaaa aaaacagacc atctctgaaa tctctgaaaa ctgataacag gccagaaaaa tccaaatgta agccactttg gggaaaagta ttttaccttg acttaccttc tgtcaccata tctgaaaaac ttcaaaagga cattaaggat ctgggagggc gagttgaaga atttctcagc aaagatatca gttatcttat ttcaaataag aaggaagcta aatttgcaca aaccttgggt cgaatttctc ctgtaccaag tccagaatct gcatatactg cagaaaccac ttcacctcat cccagccatg atggaagttc atttaagtca ccagacacag tgtgtttaag cagaggaaaa ttattagttg aaaaagctat caaggaccat gattttattc cttcaaatag tatattatca aatgccttgt catggggagt aaaaattctt catattgatg acattagata ctacattgaa caaaagaaaa aagagttgta tttactcaag aaatcaagta cttcagtaag agatgggggc aaaagagttg gtagtggtgc acaaaaaaca agaacaggaa gactcaaaaa gccttttgta aaggtggaag atatgagcca actttatagg ccattttatc ttcagctgac caatatgcct tttataaatt attctattca gaagccctgc agtccatttg atgtagacaa gccatctagt atgcaaaagc aaactcaggt taaactaaga atccaaacag atggcgataa gtatggtgga acctcaattc aactccagtt gaaagagaag aagaaaaaag gatattgtga atgttgcttg cagaaatatg aagatctaga aactcacctt ctaagtgagc aacacagaaa ctttgcacag agtaaccagt atcaagttgt tgatgatatt gtatctaagt tagtttttga ctttgtggaa tatgaaaagg acacacctaa aaagaaaaga ataaaataca gtgttggatc cctttctcct gtttctgcaa gtgtcctgaa aaagactgaa caaaaggaaa aagtggaatt gcaacatatt tctcagaaag attgccagga agatgataca acagtgaagg agcagaattt cctgtataaa gagacccagg aaactgaaaa aaagctcctg tttatttcag agcccatccc ccacccttca aatgaattga gagggcttaa tgagaaaatg agtaataaat gttccatgtt aagtacagct gaagatgaca taagacagaa ttttacacag ctacctctac ataaaaacaa acaggaatgc attcttgaca tttccgaaca cacattaagt gaaaatgact tagaagaact aagggtagat cactataaat gtaacataca ggcatctgta catgtttctg atttcagtac agataatagt ggatctcaac caaaacagaa gtcagatact gtgctttttc cagcaaagga tctcaaggaa aaggaccttc attcaatatt tactcatgat tctggtctga taacaataaa cagttcacaa gagcacctaa ctgttcaggc aaaggctcca ttccatactc ctcctgagga acccaatgaa tgtgacttca agaatatgga tagtttacct tctggtaaaa tacatcgaaa agtgaaaata atattaggac gaaatagaaa agaaaatctg gaaccaaatg ctgaatttga taaaagaact gaatttatta cacaagaaga aaacagaatt tgtagttcac cggtacagtc tttactagac ttgtttcaga ctagtgaaga gaaatcagaa tttttgggtt tcacaagcta cacagaaaag agtggtatat gcaatgtttt agatatttgg gaagaggaaa attcagataa tctgttaaca gcgtttttct cgtccccttc aacttctaca tttactggct Protein function: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7- DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. [The UniProt Consortium]