DACT2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1101 Sequence: ATGCCCCTTG AGGGTCCCCA GCAGTCTGGC AGCCTTCCAG AGGAGGGCTC CAAGCCCTCA AACAGCTGTG TCCTCAGGGA GACCATGGTG CAGGCTTCTC CCAGCTCAAA GGCCCAGCAG ACACCCTCAG CTCAGGACTA TGGACGAGGC AACATCATAT CCCCATCCAG GATGCTGGAC AAGAGCCCCT CACCGGCCTC TGGGCACTTT GCCCACCCAT CCTTTGCTGC CAGCCTGAAA ATGGGTCCCC CCAAGAGCAA GGCTGAAAAA ATCAAGAGAA GTCCCATGGA CAAGGTGCTG AGGTTTGCAA GGCAGCCGCT GCTTCTACTG GACAGGCCTG AGGGAGCCCA TGCAGCCCCC CAGCCATCCC TGGAGTGGGA CCCTGCCCAC TGGCCCACAG GGAGGGGCGG GCTCCAGCGG AGGCCAGCCC TGGCCTGGGA GGCACCCGGG CGCTCCTGTT CTGAGTCCAC CCTCTACCCC ATGCCTGTCC TCGTCCCCTT GGCAGTGGCC CCGCAGGAGA GCCACCGGAC CTCAGCCCAA GCCCTGTTCC CCTTTGAGGC GTCACTGCTC ACCTCAGTGG CCAGGAGGAA GCATCGCCGC TGGCAGTCCA CCGTGGAGAT CTCGGCCCGG GCCCGCCTGG CCAGCTGTCC TGAGTCTAAC CTGGGGCCCC CCAGGCCCGT GGCCAGGAGA GCAGGTGGCC CACTGGCCCG GGGCCGTCCC TCACTGGTCC GCCAGGACGC CTACACCAGG AGCGACTCAG AGCCCTCCAA GCACTCGGCC GAGTGTGACC CGCGGTTCCC GTCAGTCATC CCGGAGACCA GCGAGGGAGA GTCCAGTGAC CACACCACCA ACCGATTCGG AGACCGTGAG TCCAGCAGCA GCGACGAGGA GGGCGGCGCC CAGAGCAGGG ACTGTGACCT GGCACTGGGC TATGTGGCGG CCGGGCATGC GGAGCTGGCC TGGACCCAGG AGGCCCCGGT CAGCTCGGGG CCACTCCTGT CCCCCGTGCC CAAGCTGTGC CGTATTAAGG CCTCCAAGGC CCTGAAGAAG AAGATCCGCA GGTTCCAGCC GACGGCCCTG AAGGTCATGA CCATGGTGTG Protein function: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. [The UniProt Consortium]