CYP39A1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1410 Sequence: atggaactaa tttccccaac agtgattata atcctgggtt gccttgctct gttcttactc cttcagccga agaatttgcg tagacccccg tgcatcaagg gctggattcc ttggattgga gttggatttg agtttgggaa agcccctcta gaatttatag agaaagcaag aatcaagtat ggaccaatat ttacagtctt tgctatggga aaccgaatga cctttgttac tgaagaagaa ggaattaatg tgtttctaaa atccaaaaaa gtagattttg aactagcagt gcaaaatatc gtttatcgta cagcatcaat tccaaagaat gtctttttag cactgcatga aaaactctat attatgttga aagggaaaat ggggactgtc aatctccatc agtttactgg gcaactgact gaagaattac atgaacaact ggagaattta ggcactcatg ggacaatgga cctgaacaac ttagtaagac atctccttta tccagtcaca gtgaatatgc tctttaataa aagtttgttt tccacaaaca agaaaaaaat caaggagttc catcagtatt ttcaagttta tgatgaagat tttgagtatg ggtcccagtt gccagagtgt cttctaagaa actggtcaaa atccaaaaag tggttcctgg aactgtttga gaaaaacatt ccagatataa aagcatgtaa atctgcaaaa gataattcca tgacattatt gcaagctacg ctggatattg tagagacgga aacaagtaag gaaaactcac ccaattatgg gctcttactg ctttgggctt ctctgtctaa tgctgttcct gttgcatttt ggacacttgc acacgtcctt tctcatcctg atatccacaa ggccattatg gaaggcatat cttctgtgtt tggcaaagca ggcaaagata agattaaagt gtctgaggat gacctggaga atctccttct aattaaatgg tgtgttttgg aaaccattcg tttaaaagct cctggtgtca ttactagaaa agtggtgaag cctgtggaaa ttttgaatta catcattcct tctggtgact tgttgatgtt gtctccattt tggctgcata gaaatccaaa gtattttcct gagcctgaat tgttcaaacc tgaacgttgg aaaaaggcaa atttagagaa gcactctttc ttggactgct tcatggcatt tggaagcggg aagttccagt gtcctgcaag gtggtttgct ctgttagagg ttcagatgtg tattatttta atactttata aatatgactg tagtcttctg gacccattac ccaaacagag ttatctccat ttggtgggtg tcccccagcc ggaagggcaa tgccgaattg aatataaaca Protein function: A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis (PubMed:25201972, PubMed:10748047). Catalyzes 7-alpha hydroxylation of (24S)- hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver (PubMed:25201972, PubMed:10748047). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR, NADPH-ferrihemoprotein reductase) (PubMed:25201972, PubMed:10748047). [The UniProt Consortium]