CYFIP1 (Vector pUC, Accession No. BC005097)

Length: 3762 Sequence: atggcggccc aggtgactct ggaggacgcg ctgtccaacg tggacctcct ggaggagctg cccctgcccg accagcagcc ctgcatcgag cccccgccat cctcgctgct ctaccagcca aatttcaaca ctaactttga agacagaaat gcatttgtta ctggcatcgc aagatacatt gaacaagcca ccgtccactc tagcatgaac gagatgctgg aggagggcca agaatatgct gtcatgctgt acacctggag gagctgctcc cgggccatcc cacaggtgaa atgtaacgag cagcctaaca gagtggaaat ctacgagaaa accgtggagg ttctggagcc tgaggtcaca aaactgatga atttcatgta cttccagaga aatgccattg agcgtttctg cggggaagtg aggcgcctgt gccatgccga gaggaggaag gacttcgtgt cagaagccta cctgatcaca ctgggcaaat tcatcaacat gttcgctgtg ctggacgagc tgaagaacat gaagtgcagt gtgaagaacg accactcagc gtacaagagg gccgctcagt ttttacgtaa aatggcagat ccacagtcca tccaggaatc gcagaatctg tccatgttcc tggccaatca taacaagatc acacagtctc tgcagcagca gctcgaagtg atttctggct acgaagagct cctggcagat attgtgaatc tgtgtgtgga ttactacgag aacaggatgt atttgacgcc cagtgagaaa cacatgcttc tcaaagtcat gggatttggt ctgtacctga tggatgggag tgtcagtaac atctataagt tggatgccaa gaaaagaata aacttatcca aaatcgacaa gtacttcaag caactccagg tggttccact atttggggac atgcaaatag aactggcaag atatatcaag accagcgccc actacgagga aaataaatct cgatggacgt gcacatcctc cggcagcagc cctcagtaca acatctgcga gcagatgatc cagatccgcg aggaccacat gcgcttcatt tcggagctgg cgcgctacag caacagcgag gtggtcacgg gctcgggccg ccaggaggcc cagaagacgg acgcggagta ccgcaagctc ttcgacctgg cgctgcaggg cctgcagctg ttgtcgcagt ggagcgcgca cgtgatggaa gtgtattcct ggaagcttgt gcaccccacc gacaagtact ccaacaagga ctgccccgac agcgctgaag agtacgagcg tgccacgcgc tacaactaca ccagcgagga gaagtttgcc ctagtggagg tgatcgccat gatcaaaggc ctgcaggtgc tgatgggcag gatggagagc gtgttcaacc acgccatccg gcacaccgtc tatgccgcac tgcaggactt ctcccaggtg acccttaggg agccgctgcg gcaggccatc aagaagaaga agaacgtcat ccagagtgtc ctgcaggcca tcaggaagac cgtgtgtgac tgggagacgg ggcatgagcc cttcaatgac ccagccttgc ggggcgagaa ggaccccaag agcggcttcg acataaaagt accacgccgc gccgtgggac cctccagcac tcagctttac atggtgagaa ccatgctaga gtccctcatt gcagacaaaa gtggttccaa gaaaaccttg agaagtagcc ttgaggggcc caccatattg gacatagaaa aatttcatcg agagtcattc ttctacactc acttgataaa tttcagtgaa acgctgcagc agtgctgtga cctttcgcag ctgtggttcc gagagttctt cctggagctg accatgggca ggaggatcca gttccccatt gagatgtcga tgccctggat cctgacggac cacatcctgg agaccaagga ggcatcgatg atggagtacg tgctctactc cctggacctg tacaatgaca gcgcccacta cgcgctcacc aggttcaaca agcagttcct gtacgacgaa attgaggccg aggtgaatct atgttttgac caatttgttt acaagctagc agaccagata tttgcctatt ataaggttat ggcaggaagt ttgcttcttg ataaacggtt acgatcagaa tgcaagaatc agggagccac gatccacctc ccgccgtcta accgctacga gacgctgctg aagcagaggc atgtgcagct cctcggcaga tcaatagacc tcaatcgtct gatcacccag cgcgtctcag cagccatgta taagtcccta gaactggcga ttggacgatt tgaaagtgaa gatttgacct ccatagttga gctggatggc ctgttggaaa tcaaccgcat gacccacaag ctgctgagcc ggtacctgac gctggacggc ttcgacgcca tgttccggga ggccaaccac aacgtgtcag cgccctacgg gaggatcacc ctgcacgtct tctgggagct caactatgac ttcctgccca actactgcta caacggctct accaaccggt ttgttcggac agtgttacca ttttctcagg aatttcaaag agataagcag cctaatgcac agcctcagta tctgcatgga tccaaggctt tgaacttggc ctactccagc atttacggca gctaccggaa cttcgtggga cctccacact ttcaagtcat ctgccggctt ctcggctacc agggtatcgc cgtggtcatg gaggagctgc tgaaggtcgt caagagcctg ctgcaaggca caatcctgca gtacgtgaag acgctgatgg aggtgatgcc caagatctgc cgcctgcccc ggcacgagta cggctctcct ggtatcctgg agttcttcca ccaccagctg aaggacatcg tggagtacgc agagctgaag acggtgtgct tccagaacct gcgggaggtg gggaacgcca tcctcttctg cctgctcatc gagcagagcc tgtctttaga agaagtgtgt gacctgctgc acgcggctcc tttccagaac atcttgccgc gagtccatgt gaaagagggg gagagacttg atgccaaaat gaaaagacta gaatcaaagt acgccccgct gcatcttgtc ccactgattg aaagactggg gacccctcag caaattgcca tcgcaagaga gggggacctg ctgacaaagg agcgcctctg ctgcggcctg tccatgtttg aggtcatcct gacacggatc cggagctttc tggatgaccc catctggcgc gggcctctgc ccagcaatgg ggtcatgcat gtggacgagt gtgtggagtt tcacagactg tggagtgcca tgcagtttgt ctactgcatt cccgtgggga cacacgagtt cacagtcgag cagtgctttg gtgatgggct acactgggct ggctgtatga tcatcgtact tcttgggcag cagcggcgtt ttgctgtgct ggatttctgc taccatctac ttaaagtcca gaaacatgat ggcaaagatg agattattaa aaatgtgcct ttgaagaaga tggtggagag aattcgcaag ttccagattc tcaatgatga gatcatcacc atcctggata agtacctgaa gtcaggcgac ggggagggca cgccagtgga gcatgtgcgc tgcttccagc cgcccatcca ccagtccctc gccagcagct Protein function: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E- FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. May act as an invasion suppressor in cancers. [The UniProt Consortium]