CXXC5 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 684 Sequence: atgatgggcg gagagtctgc tgacaaggcc actgcggctg cagccgctgc ctccctgttg gccaatgggc atgacctggc ggcggccatg gcggtggaca aaagcaaccc tacctcaaag cacaaaagtg gtgctgtggc cagcctgctg agcaaggcag agcgggccac ggagctggca gccgagggac agctgacgct gcagcagttt gcgcagtcca cagagatgct gaagcgcgtg gtgcaggagc atctcccgct gatgagcgag gcgggtgctg gcctgcctga catggaggct gtggcaggtg ccgaagccct caatggccag tccgacttcc cctacctggg cgctttcccc atcaacccag gcctcttcat tatgaccccg gcaggtgtgt tcctggccga gagcgcgctg cacatggcgg gcctggctga gtaccccatg cagggagagc tggcctctgc catcagctcc ggcaagaaga agcggaaacg ctgcggcatg tgcgcgccct gccggcggcg catcaactgc gagcagtgca gcagttgtag gaatcgaaag actggccatc agatttgcaa attcagaaaa tgtgaggaac tcaaaaagaa gccttccgct gctctggaga aggtgatgct tccgacggga gccgccttcc ggtggtttca Protein function: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (PubMed:29276034). [The UniProt Consortium]