CTDSP2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 816 Sequence: atggaacacg gctccatcat cacccaggcg cggagggaag acgccctggt gctcaccaag caaggcctgg tctccaagtc ctctcctaag aagcctcgtg gacgtaacat cttcaaggcc cttttctgct gttttcgcgc ccagcatgtt ggccagtcaa gttcctccac tgagctcgct gcgtataagg aggaagcaaa caccattgct aagtcggatc tgctccagtg tctccagtac cagttctacc agatcccagg gacctgcctg ctcccagagg tgacagagga agatcaagga aggatctgtg tggtcattga cctcgatgaa acccttgtgc atagctcctt taagccaatc aacaatgctg acttcatagt gcctatagag attgagggga ccactcacca ggtgtatgtg ctcaagaggc cttatgtgga tgagttcctg agacgcatgg gggaactctt tgaatgtgtt ctcttcactg ccagcctggc caagtatgcc gaccctgtga cagacctgct ggaccggtgt ggggtgttcc gggcccgcct attccgtgag tcttgcgtgt tccaccaggg ctgctacgtc aaggacctca gccgcctggg gagggacctg agaaagaccc tcatcctgga caactcgcct gcttcttaca tattccaccc cgagaatgca gtgcctgtgc agtcctggtt tgatgacatg gcagacactg agttgctgaa cctgatccca atctttgagg agctgagcgg agcagaggac gtctacacca gccttgggca gctgcgggcc Protein function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. [The UniProt Consortium]