CTDSP1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 786 Sequence: atggacagct cggccgtcat tactcagatc agcaaggagg aggctcgggg cccgctgcgg ggcaaaggtg accagaagtc agcagcttcc cagaagcccc gaagccgggg catcctccac tcactcttct gctgtgtctg ccgggatgat ggggaggccc tgcctgctca cagcggggcg cccctgcttg tggaggagaa tggagccatc cctaagcaga ccccagtcca atacctgctc cctgaggcca aggcccagga ctcagacaag atctgcgtgg tcatcgacct ggacgagacc ctggtgcaca gctccttcaa gccagtgaac aacgcggact tcatcatccc tgtggagatt gatggggtgg tccaccaggt ctacgtgttg aagcgtcctc acgtggatga gttcctgcag cgaatgggcg agctctttga atgtgtgctg ttcactgcta gcctcgccaa gtacgcagac ccagtagctg acctgctgga caaatggggg gccttccggg cccggctgtt tcgagagtcc tgcgtcttcc accgggggaa ctacgtgaag gacctgagcc ggttgggtcg agacctgcgg cgggtgctca tcctggacaa ttcacctgcc tcctatgtct tccatccaga caatgctgta ccggtggcct cgtggtttga caacatgagt gacacagagc tccacgacct cctccccttc ttcgagcaac tcagccgtgt ggacgacgtg tactcagtgc tcaggcagcc acggccaggg Protein function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. [The UniProt Consortium]