CSGALNACT1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or

Length: 894 Sequence: atgatgatgg ttcgccgggg gctgcttgcg tggatttccc gggtggtggt tttgctggtg ctcctctgct gtgctatctc tgtcctgtac atgttggcct gcaccccaaa aggtgacgag gagcagctgg cactgcccag ggccaacagc cccacgggga aggaggggta ccaggccgtc cttcaggagt gggaggagca gcaccgcaac tacgtgagca gcctgaagcg gcagatcgca cagctcaagg aggagctgca ggagaggagt gagcagctca ggaatgggca gtaccaagcc agcgatgctg ctggcctggg tctggacagg agccccccag agaaaaccca ggccgacctc ctggccttcc tgcactcgca ggtggacaag gcagaggtga atgctggcgt caagctggcc acagagtatg cagcagtgcc tttcgatagc tttactctac agaaggtgta ccagctggag actggcctta cccgccaccc cgaggagaag cctgtgagga aggacaagcg ggatgagttg gtggaagcca ttgaatcagc cttggagacc ctgaacaatc ctgcagagaa cagccccaat caccgtcctt acacggcctc tgatttcata gaagggatct accgaacaga aagggacaaa gggacattgt atgagctcac cttcaaaggg gaccacaaac atgaattcaa acggctcatc ttatttcgac cattcggccc catcatgaaa gtggaaaatg aaaagctcaa catggccaac acgcttatca atgttatcgt gcctctagca aaaagggtgg acaagttccg gcagttcatg cagaatttca ggcctgctga tgaagttttt agatgtgtgc ctttaagccc Protein function: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification (PubMed:11788602, PubMed:12163485, PubMed:12446672, PubMed:17145758). Moreover, is involved in the metabolism of aggrecan. [The UniProt Consortium]