CPEB4 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2190 Sequence: atgggggatt acgggtttgg agtgctagtg caaagcaata ctgggaataa atctgctttt ccagtcagat tccatccaca tctgcagcct ccacaccatc accaaaatgc cacccccagc cctgctgctt ttataaataa taacacagct gccaatggca gcagtgctgg gtcagcttgg ctttttcctg ctccagctac ccataacatt caggatgaga tcttggggtc agaaaaagca aaaagtcagc aacaggaaca gcaagacccc ttagaaaagc agcagctttc cccaagtcca ggtcaggaag ctggaatact gcctgaaaca gagaaggcaa aatcagaaga aaatcaaggg gacaattctt cggaaaatgg caatgggaag gagaaaataa ggatcgaatc tccagtgttg acagggtttg attatcaaga agccactggg ctaggtactt caacccaacc cttgacatct agcgcatcgt ctcttactgg tttcagtaac tggtcagcag cgatagcgcc ttcctcctct acaataatca atgaagatgc aagtttcttt caccagggag gggtccctgc tgcttcggct aataacggtg ctctgttgtt tcaaaatttc ccccatcatg tcagccctgg ctttggaggc agcttctctc ctcagatcgg gcctctctca cagcaccacc cacatcaccc tcatttccag catcatcaca gccagcatca gcagcaaagg aggtctcctg ccagtcccca tcccccaccc ttcacacata gaaatgctgc ttttaaccag ctgcctcatt tggcgaataa tcttaacaaa cccccctctc cgtggagcag ctaccagagt ccgtcaccaa caccctcctc ttcctggagc ccgggcggtg gtggatatgg tggctgggga ggttcccaag gccgagatca ccgcagaggg ctgaatggtg gaataacgcc cctgaactcc atctcgcctt tgaagaaaaa ttttgcaagc aatcatattc agctccagaa gtatgctcgc cccagctctg cctttgcacc taaatcctgg atggaagata gcttgaacag ggctgacaac atttttcctt ttccggatcg ccccaggaca ttcgacatgc actcactgga gagttcactc attgacataa tgagagctga aaatgatacc attaaaggtc gtctaaacta ttcatatcca ggatccgata gctctctgct tattaatgca aggacatatg ggcgaaggag aggtcagtct tcactgtttc caatggaaga tggattcttg gatgatggcc gtggggatca gcctcttcat agtggcctgg gttcacctca ctgcttcagt caccagaatg gggaaagagt ggaacgatat tctcgaaagg tgtttgtagg cggattgcct ccagacattg atgaagatga gatcacagct agttttcgtc gctttggccc tctgattgtg gattggcctc ataaagctga gagcaaatcc tattttcctc ctaaaggcta tgcattcctg ctgtttcaag atgaaagctc tgtgcaggct ctcattgatg catgcattga agaagatgga aaactctacc tttgtgtatc aagtcccact atcaaggata agccagtcca gattcggcct tggaatctca gtgacagtga ctttgtgatg gatggttcac agccacttga cccacgaaaa actatatttg ttggtggtgt tcctcgacca ttacgagctg tggagcttgc gatgataatg gatcggctat atggaggtgt gtgctacgct gggattgata ccgaccctga gctaaaatac ccaaaaggag ctgggagagt tgcgttctct aatcaacaga gttacatagc tgctatcagt gcccgctttg ttcagctgca gcatggagag atagataaac gggtggaagt taagccatat gtcttggatg atcagctgtg tgatgaatgt cagggggccc gttgtggggg gaaatttgct ccatttttct gtgctaatgt tacctgtctg cagtattact gtgaatattg ctgggctgct atccattctc gtgctggcag ggaattccac aagcccctgg tgaaggaagg cggtgaccgc cctcggcata tttcattccg Protein function: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE- regulated mRNAs in conditions in which global protein synthesis is inhibited. Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory. [The UniProt Consortium]