CLCN7 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2418 Sequence: atggccaacg tctctaagaa ggtgtcctgg tccggccggg accgggacga cgaggaggcg gcgccgctgc tgcggaggac ggcgcggccc ggcgggggga cgccgctgct gaacggggct gggcctgggg ctgcgcgcca gtcaccacgt tctgcgcttt tccgagtcgg acatatgagc agcgtggagc tggatgatga acttttggac ccggatatgg accctccaca tcccttcccc aaggagatcc cacacaacga gaagctcctg tccctcaagt atgagagctt ggactatgac aacagtgaga accagctgtt cctggaggag gagcggcgga tcaatcacac ggccttccgg acggtggaga tcaagcgctg ggtcatctgc gccctcattg ggatcctcac gggcctcgtg gcctgcttca ttgacatcgt ggtggaaaac ctggctggcc tcaagtacag ggtcatcaag ggcaatatcg acaagttcac agagaagggc ggactgtcct tctccctgtt gctgtgggcc acgctgaacg ccgccttcgt gctcgtgggc tctgtgattg tggctttcat agagccggtg gctgctggca gcggaatccc ccagatcaag tgcttcctca acggggtgaa gatcccccac gtggtgcggc tcaagacgtt ggtgatcaaa gtgtccggtg tgatcctgtc cgtggtcggg ggcctggccg tgggaaagga agggccgatg atccactcag gttcagtgat tgccgccggg atctctcagg gaaggtcaac gtcactgaaa cgagatttca agatcttcga gtacttccgc agagacacag agaagcggga cttcgtctcc gcaggggctg cggccggagt gtcagcggcg tttggagccc ccgtgggtgg ggtcctgttc agcttggagg agggtgcgtc cttctggaac cagttcctga cctggaggat cttctttgct tccatgatct ccacgttcac cctgaatttt gttctgagca tttaccacgg gaacatgtgg gacctgtcca gcccaggcct catcaacttc ggaaggtttg actcggagaa aatggcctac acgatccacg agatcccggt cttcatcgcc atgggcgtgg tgggcggtgt gcttggagca gtgttcaatg ccttgaacta ctggctgacc atgtttcgaa tcaggtacat ccaccggccc tgcctgcagg tgattgaggc cgtgctggtg gccgccgtca cggccacagt tgccttcgtg ctgatctact cgtcgcggga ttgccagccc ctgcaggggg gctccatgtc ctacccgctg cagctctttt gtgcagatgg cgagtacaac tccatggctg cggccttctt caacaccccg gagaagagcg tggtgagcct cttccacgac ccgccaggct cctacaaccc cctgaccctc ggcctgttca cgctggtcta cttcttcctg gcctgctgga cctacgggct cacggtgtct gccggggtct tcatcccgtc cctgctcatc ggggctgcct ggggccggct ctttgggatc tccctgtcct acctcacggg ggcggcgatc tgggcggacc ccggcaaata cgccctgatg ggagctgctg cccagctggg cgggattgtg cggatgacac tgagcctgac cgtcatcatg atggaggcca ccagcaacgt gacctacggc ttccccatca tgctggtgct catgaccgcc aagatcgtgg gcgacgtctt cattgagggc ctgtacgaca tgcacattca gctgcagagt gtgcccttcc tgcactggga ggccccggtc acctcacact cactcactgc cagggaggtg atgagcacac cagtgacctg cctgaggcgg cgtgagaagg tcggcgtcat tgtggacgtg ctgagcgaca cggcgtccaa tcacaacggc ttccccgtgg tggagcatgc cgatgacacc cagcctgccc ggctccaggg cctgatcctg cgctcccagc tcatcgttct cctaaagcac aaggtgtttg tggagcggtc caacctgggc ctggtacagc ggcgcctgag gctgaaggac ttccgagacg cctacccgcg cttcccaccc atccagtcca tccacgtgtc ccaggacgag cgggagtgca ccatggacct ctccgagttc atgaacccct ccccctacac ggtgccccag gaggcgtcgc tcccacgggt gttcaagctg ttccgggccc tgggcctgcg gcacctggtg gtggtggaca accgcaatca ggttgtcggg ttggtgacca ggaaggacct cgccaggtac cgcctgggaa agagaggctt ggaggagctc tcgctggccc Protein function: Slowly voltage-gated channel mediating the exchange of chloride ions against protons (PubMed:18449189, PubMed:21527911). Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH (PubMed:18449189, PubMed:21527911, PubMed:31155284). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. [The UniProt Consortium]