CLASP2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1296 Sequence: atgaggcgac tgatttgcaa acggatctgt gattataaaa gcttcgatga tgaagaatca gtggatggaa ataggccatc atcagctgca tcagccttca aggttcctgc acctaaaaca tccggaaatc ctgccaacag tgcaaggaag cctggttcag caggtggccc taaggttgga ggtgcttcta aggaaggagg tgctggagca gttgatgaag atgattttat aaaagctttt acagatgtcc cttctattca gatttattct agtcgagaac tcgaagaaac attaaataaa atcagggaaa ttttgtcaga tgataaacat gactgggatc agcgtgccaa tgcactgaag aaaattcgat cactgcttgt tgctggagct gcacagtatg attgcttttt tcaacattta cgattgttgg atggagcact taaactttca gctaaggatc ttagatccca ggtggttaga gaagcttgta ttactgtagc ccacctttca acagttttgg gaaacaagtt tgatcatggc gctgaagcca ttgtacctac actttttaat ctcgtcccca atagtgcaaa agtcatggca acttctggat gtgcagcaat cagatttatc attcggcata ctcatgtacc cagacttata cctttaataa caagcaattg cacatcaaaa tcagttcccg tgaggagacg ttcatttgaa tttttagatt tattgttgca agagtggcag actcattcat tggaaagaca tgcagccgtc ttggttgaaa ctattaaaaa gggaattcat gatgctgacg ctgaggccag agtggaggca agaaagacat acatgggtct tagaaaccac tttcctggtg aagctgaaac attatataat tcccttgagc catcttatca gaagagtctt caaacttact taaagagttc tggcagtgta gcatctcttc cacaatcaga caggtcctca tccagctcac aggaaagtct caatcgccct ttttcttcca aatggtctac agcaaatcca tcaactgtgg ctggaagagt atcagcaggc agcagcaaag ccagttccct tccaggaagc ctgcagcgtt cacgaagtga cattgatgtg aatgctgctg caggtgccaa ggcacatcat gctgctggac agtctgtgcg aagcgggcgc ttaggtgcag gtgccctgaa tgcaggttcc tatgcgtcac tagaatgtga agccttttgg agatctggga gaactgcaaa gctctactct Protein function: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2- dependent stabilization of microtubules at the cell cortex. [The UniProt Consortium]