CIRH1A (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2061 Sequence: atgggtgaat ttaaggtcca tcgagtacgt ttctttaatt atgttccatc aggaatccgc tgtgtggctt acaataacca gtcaaacaga ttggctgttt cacgaacaga tggcactgtg gaaatttata acttgtcagc aaactacttt caggagaaat ttttcccagg tcatgagtct cgggctacag aagctttgtg ctgggcagaa ggacagcgac tctttagtgc tgggctcaat ggcgagatta tggagtatga tttacaggcg ttaaacatca agtatgctat ggatgccttt ggaggaccta tttggagcat ggctgccagc cccagtggct ctcaactttt ggttggttgt gaagatggat ctgtgaaact atttcaaatt accccagaca aaatccagtt tgaaagaaat tttgatcggc agaaaagtcg catcctgagt ctcagctggc atccctctgg tacccacatt gcagctggtt ccatagacta cattagtgtg tttgatgtca aatcaggcag cgctgttcat aagatgattg tggacaggca gtatatgggc gtgtctaagc ggaagtgcat cgtgtggggt gtcgccttct tgtccgatgg cactatcata agtgtggact ctgctgggaa ggtgcagttc tgggactcag ccactgggac gcttgtgaag agccatctca tcgctaatgc tgacgtgcag tccattgctg tagctgacca agaagacagt ttcgtggtgg gcacagccga gggaacagtc ttccattttc agctggtccc tgtgacatct aacagcagtg agaagcagtg ggtgcggaca aaaccgttcc agcatcacac tcatgacgtg cgcactgtgg cccacagccc aacagcgctg atatctggag gcactgacac ccacttagtc tttcgtcctc tcatggagaa ggtggaagta aagaattacg atgccgctct ccgaaaaatc acctttcccc accgatgtct catctcctgt tctaaaaaga ggcagcttct cctcttccag tttgctcatc acttagaact ttggcgactg ggatccacag ttgcaacagg caagaatggg gatactcttc cactctctaa aaatgcagat catttactgc acctaaagac aaagggtcct gagaacatta tctgtagctg tatctcccca tgtggaagtt ggatagccta ttctacagtt tctcggtttt ttctctatcg gctgaattat gaacatgaca acataagcct caaaagggtt tccaaaatgc cagcattcct tcgctctgcc cttcagattt tgttttctga agattcaaca aagctctttg tagcatcaaa tcaaggagct ctgcatattg ttcagctgtc aggaggaagc ttcaagcacc tgcatgcttt ccagcctcag tcaggaacag tggaggccat gtgtcttttg gcagtcagtc cagatgggaa ttggctagct gcatcaggta ccagtgctgg agtccatgtc tacaacgtaa aacagctaaa gcttcactgc acggtgcctg cttacaattt cccagtgact gctatggcta ttgcccccaa taccaacaac cttgtcatcg ctcattcgga ccagcaggta tttgagtaca gcatcccaga caaacagtat acagattgga gccggactgt ccagaagcag ggctttcacc acctttggct ccaaagggat actcctatca cacacatcag ttttcatccc aagagaccga tgcacatcct tctccatgat gcctacatgt tctgcatcat tgacaagtca ttgccccttc caaatgacaa aaccttactc tacaatccat ttcctcccac gaatgaatca gatgtcatcc ggaggcgcac agctcatgct tttaaaattt ctaagatata taagcctcta ctcttcatgg atcttttgga tgaaagaaca ctcgtggcag tagaacggcc tctggatgac atcattgctc agctcccacc acccattaaa aagaagaaat ttggaaccta Protein function: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre- ribosomal RNA transcription by RNA polymerase (PubMed:17699751, PubMed:19732766). May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (PubMed:19732766). [The UniProt Consortium]