CHRNA9 (Vector pENTR223.1, Accession No. BC113549)

Length: 1440 Sequence: atgaactggt cccattcctg catctccttt tgctggatct actttgctgc ttccagactg agagctgcag agacggcaga tggaaaatat gctcagaagt tgtttaatga cctttttgaa gattattcta atgctcttcg tccagtggaa gatacagata aagtcctgaa tgtgaccctg cagattacgc tctctcagat taaggatatg gatgaaagaa accaaattct gactgcttat ttgtggatcc gccaaatctg gcacgatgcc tatctcacgt gggaccgaga tcagtacgat ggcctagact ccatcaggat ccccagtgac ctcgtgtgga ggccagacat cgtcttatat aacaaggctg atgatgaatc ttcagagcct gtgaacacca atgtggtcct gcggtatgat gggctgatca cctgggatgc accggccatc accaaaagct cctgtgtggt ggatgtcacc tacttccctt ttgacaacca gcagtgcaac ctgacttttg gttcctggac ctacaatggc aatcaggtgg acatattcaa cgccttggac agcggagatc tctctgactt cattgaagat gtggaatggg aggtccatgg catgcccgct gtgaagaatg tgatctccta tggctgctgc tctgagcctt acccggatgt cacattcacc ctccttctga agaggaggtc ctcgttctat atcgtcaacc tcctcatccc atgcgtcctc atatcttttc tggctcctct gagtttttat ctcccagcag cctccggaga aaaggtctcc ctgggagtga ccatcctgtt ggccatgact gtatttcagc taatggtggc agaaatcatg ccggcctcag aaaatgtgcc cctgataggt aaatactaca tagccacgat ggccctgatc acagcctcca ctgcgttgac catcatggtg atgaatatcc acttctgtgg ggccgaggcc cggccggtgc cacactgggc cagggtggtc atcctgaaat acatgtccag ggtcttgttt gtctatgatg tgggtgaaag ctgcctcagc ccgcaccaca gtagagagcg ggaccacctc acgaaagttt atagcaaact cccagagtct aacctgaaag cagccaggaa caaagacctt tccagaaaga aggacatgaa caaacgctta aagaacgacc tgggctgcca gggtaagaac cctcaggagg ccgagagtta ctgtgcacag tacaaagtgc tgacgaggaa tattgagtac atcgccaagt gcctcaaaga ccacaaggcc accagttcca aggggagtga atggaagaag gtggcgaaag tcatagaccg attcttcatg tggatttttt tcattatggt gtttgtgatg actattttga tcatagcaag Protein function: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840). [The UniProt Consortium]