CENPN (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1018 Sequence: atggatgaga ctgttgctga gttcatcaag aggaccatct tgaaaatccc catgaatgaa ctgacaacaa tcctgaaggc ctgggatttt ttgtctgaaa atcaactgca gactgtaaat ttccgacaga gaaaggaatc tgtagttcag cacttgatcc atctgtgtga ggaaaagcgt gcaagtatca gtgatgctgc cctgttagac atcatttata tgcaatttca tcagcaccag aaagtttggg atgtttttca gatgagtaaa ggaccaggtg aagatgttga cctttttgat atgaaacaat ttaaaaattc gttcaagaaa attcttcaga gagcattaaa aaatgtgaca gtcagcttca gagaaactga ggagaatgca gtctggattc gaattgcctg gggaacacag tacacaaagc caaaccagta caaacctacc tacgtggtgt actactccca gactccgtac gccttcacgt cctcctccat gctgaggcgc aatacaccgc ttctgggtca ggcgctgaca attgctagca aacaccatca gattgtgaaa atggacctga gaagtcggta tctggactct cttaaggcta ttgtttttaa acagtataat cagacctttg aaactcacaa ctctacgaca cctctacagg aaagaagcct tggactagat ataaatatgg attcaaggat cattcatgaa aacatagtag aaaaagagag agtccaacga ataactcaag aaacatttgg agattatcct caaccacaac tagaatttgc acaatataag cttgaaacga aattcaaaag tggtttaaat gggagcatct tggctgagag ggaagaaccc ctccgatgcc taataaagtt ctctagccca catcttctgg aagcattgaa atccttagca ccagcgggta ttgcagatgc tccactttct ccactgctca cttgcatacc caacaagaga atgaattatt ttaaaattag Protein function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. [The UniProt Consortium]